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Author Topic:   Rebuttal To Creationists - "Since We Can't Directly Observe Evolution..."
Kleinman
Member (Idle past 365 days)
Posts: 2142
From: United States
Joined: 10-06-2016


Message 1906 of 2932 (902142)
11-18-2022 10:55 AM
Reply to: Message 1904 by Taq
11-18-2022 10:47 AM


Kleinman:
You are a liar. You never did the mathematics of any real experiment.
Taq:
The mathematics are in the paper. Are you denying the results published in the paper?

A dimwit like you thinks that a constant environment exists for 90 generations. And you have no idea what a virus does to a cell, but you think you would when you post a link about koalas that may go extinct from a single retroviral infection. It damages their immune system, you dummy. You suck as a virologist. All you do is hurt people.

This message is a reply to:
 Message 1904 by Taq, posted 11-18-2022 10:47 AM Taq has replied

Replies to this message:
 Message 1908 by Taq, posted 11-18-2022 11:01 AM Kleinman has replied
 Message 1910 by Tanypteryx, posted 11-18-2022 11:12 AM Kleinman has replied

  
ringo
Member (Idle past 441 days)
Posts: 20940
From: frozen wasteland
Joined: 03-23-2005


Message 1907 of 2932 (902143)
11-18-2022 10:56 AM
Reply to: Message 1905 by Kleinman
11-18-2022 10:49 AM


Re: Kleinman does not know asexual vs sexual
Kleinman writes:
ringo writes:
And you STILL have no substantive response.
Nothing that an amateur like you would understand.
According to you, NOBODY understands, so I'm in good company.

Come all of you cowboys all over this land,
I'll teach you the law of the Ranger's Command:
To hold a six shooter, and never to run
As long as there's bullets in both of your guns.
-- Woody Guthrie

This message is a reply to:
 Message 1905 by Kleinman, posted 11-18-2022 10:49 AM Kleinman has replied

Replies to this message:
 Message 1909 by Kleinman, posted 11-18-2022 11:08 AM ringo has replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(3)
Message 1908 of 2932 (902145)
11-18-2022 11:01 AM
Reply to: Message 1906 by Kleinman
11-18-2022 10:55 AM


Kleinman writes:
A dimwit like you thinks that a constant environment exists for 90 generations.
So why ask for real biological examples if all you are going to do is have a fit and throw toys from your pram?
You talk up and down about the Lenski and Kishony experiment even though they had constant environments for way more than 90 generations. Suddenly, there's an experiment with results you don't like, and only then are constant environments a problem. Go figure.

This message is a reply to:
 Message 1906 by Kleinman, posted 11-18-2022 10:55 AM Kleinman has replied

Replies to this message:
 Message 1911 by Kleinman, posted 11-18-2022 11:17 AM Taq has replied

  
Kleinman
Member (Idle past 365 days)
Posts: 2142
From: United States
Joined: 10-06-2016


Message 1909 of 2932 (902146)
11-18-2022 11:08 AM
Reply to: Message 1907 by ringo
11-18-2022 10:56 AM


Re: Kleinman does not know asexual vs sexual
Kleinman:
Nothing that an amateur like you would understand.
ringo:
According to you, NOBODY understands, so I'm in good company.

To you, good company doesn't understand biological evolution. Kishony doesn't explain his own experiment, Lenski doesn't know why biological competition slows adaptation and doesn't explain his own experiment, and Desai is still trying to figure out how bacteria evolve drug resistance. What good is that company? They can't explain biological evolution and they can't explain the evolution of drug resistance and why cancer treatments fail. You keep that company, it will make you feel so smart but they can't explain anything.

This message is a reply to:
 Message 1907 by ringo, posted 11-18-2022 10:56 AM ringo has replied

Replies to this message:
 Message 1915 by ringo, posted 11-18-2022 11:47 AM Kleinman has replied

  
Tanypteryx
Member
Posts: 4451
From: Oregon, USA
Joined: 08-27-2006
Member Rating: 5.0


Message 1910 of 2932 (902149)
11-18-2022 11:12 AM
Reply to: Message 1906 by Kleinman
11-18-2022 10:55 AM


So Conman the Bullshitter still can't produce any evidence to refute the pattern of ERVs, only lunatic ravings. Next he will rave about how he cured every disease and saved us all.

Stop Tzar Vladimir the Condemned!

What if Eleanor Roosevelt had wings? -- Monty Python

One important characteristic of a theory is that is has survived repeated attempts to falsify it. Contrary to your understanding, all available evidence confirms it. --Subbie

If evolution is shown to be false, it will be at the hands of things that are true, not made up. --percy

The reason that we have the scientific method is because common sense isn't reliable. -- Taq


This message is a reply to:
 Message 1906 by Kleinman, posted 11-18-2022 10:55 AM Kleinman has replied

Replies to this message:
 Message 1912 by Kleinman, posted 11-18-2022 11:22 AM Tanypteryx has replied

  
Kleinman
Member (Idle past 365 days)
Posts: 2142
From: United States
Joined: 10-06-2016


Message 1911 of 2932 (902150)
11-18-2022 11:17 AM
Reply to: Message 1908 by Taq
11-18-2022 11:01 AM


Kleinman:
A dimwit like you thinks that a constant environment exists for 90 generations.
Taq:
So why ask for real biological examples if all you are going to do is have a fit and throw toys from your pram?

You talk up and down about the Lenski and Kishony experiment even though they had constant environments for way more than 90 generations. Suddenly, there's an experiment with results you don't like, and only then are constant environments a problem. Go figure.

The Kishony and Lenski experiments demonstrate exactly how descent with modification operates. The Desai experiment demonstrates how recombination works in a constant environment. Descent with modification depends on the number of replications a particular variant can do. Many factors can slow the accumulation of these replications. Desai created a special environment that increases the frequencies of adaptive alleles. You are so stupid that you think this contrived environment exists in real environments. That's why you don't and haven't done any mathematics of biological evolutionary processes. It doesn't fit your stupid narrative.

This message is a reply to:
 Message 1908 by Taq, posted 11-18-2022 11:01 AM Taq has replied

Replies to this message:
 Message 1913 by Taq, posted 11-18-2022 11:27 AM Kleinman has replied

  
Kleinman
Member (Idle past 365 days)
Posts: 2142
From: United States
Joined: 10-06-2016


Message 1912 of 2932 (902151)
11-18-2022 11:22 AM
Reply to: Message 1910 by Tanypteryx
11-18-2022 11:12 AM


Tanypteryx:
So Conman the Bullshitter still can't produce any evidence to refute the pattern of ERVs, only lunatic ravings. Next he will rave about how he cured every disease and saved us all.
The bug chaser thinks that a germline infected with 200k retroviruses causes no harm. And the bug chaser hasn't cured any diseases, he only causes them. Thanks a lot, dummy. Your stupidity is dangerous.

This message is a reply to:
 Message 1910 by Tanypteryx, posted 11-18-2022 11:12 AM Tanypteryx has replied

Replies to this message:
 Message 1914 by Tanypteryx, posted 11-18-2022 11:47 AM Kleinman has replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(1)
Message 1913 of 2932 (902152)
11-18-2022 11:27 AM
Reply to: Message 1911 by Kleinman
11-18-2022 11:17 AM


Kleinman writes:
The Kishony and Lenski experiments demonstrate exactly how descent with modification operates.
The Lenski experiment had a constant environment for 10's of thousands of generations. Are you saying that a constant environment does not disqualify an experiment?
Desai created a special environment that increases the frequencies of adaptive alleles.
How was the Desai experiment any different than the Kishony/Lenski experiment with regard to environments that increase the frequency of adaptive alleles?
Also, the asexual and sexual populations in the Desai experiment were in the same environment. Clonal interference was only seen in the asexual population, not in the sexual population even though they were in the same environment. It wasn't the constant environment that caused the removal of clonal interference in the sexual population. It was recombination that alleviated clonal interference.
Descent with modification depends on the number of replications a particular variant can do.
It also depends on the existence of sexual recombination, as shown in the Desai experiment.

This message is a reply to:
 Message 1911 by Kleinman, posted 11-18-2022 11:17 AM Kleinman has replied

Replies to this message:
 Message 1916 by Kleinman, posted 11-18-2022 11:51 AM Taq has replied

  
Tanypteryx
Member
Posts: 4451
From: Oregon, USA
Joined: 08-27-2006
Member Rating: 5.0


Message 1914 of 2932 (902154)
11-18-2022 11:47 AM
Reply to: Message 1912 by Kleinman
11-18-2022 11:22 AM


So still no evidence, just handwaving and blaming others for your own failures. Thanks a lot Bullshit Peddler.

Stop Tzar Vladimir the Condemned!

What if Eleanor Roosevelt had wings? -- Monty Python

One important characteristic of a theory is that is has survived repeated attempts to falsify it. Contrary to your understanding, all available evidence confirms it. --Subbie

If evolution is shown to be false, it will be at the hands of things that are true, not made up. --percy

The reason that we have the scientific method is because common sense isn't reliable. -- Taq


This message is a reply to:
 Message 1912 by Kleinman, posted 11-18-2022 11:22 AM Kleinman has replied

Replies to this message:
 Message 1917 by Kleinman, posted 11-18-2022 11:53 AM Tanypteryx has not replied

  
ringo
Member (Idle past 441 days)
Posts: 20940
From: frozen wasteland
Joined: 03-23-2005


Message 1915 of 2932 (902155)
11-18-2022 11:47 AM
Reply to: Message 1909 by Kleinman
11-18-2022 11:08 AM


Re: Kleinman does not know asexual vs sexual
Kleinman writes:
To you, good company doesn't understand biological evolution.
Huh? I respect and admire biologists. You're the one who claims they don't know what they're doing.
Kleinman writes:
Kishony doesn't explain his own experiment, Lenski doesn't know why biological competition slows adaptation and doesn't explain his own experiment, and Desai is still trying to figure out how bacteria evolve drug resistance.
Do they agree with you?
Kleinman writes:
What good is that company?
Consensus is good company.
Kleinman writes:
They can't explain biological evolution and they can't explain the evolution of drug resistance and why cancer treatments fail.
But they can and do.
Kleinman writes:
You keep that company...
Thanks. I will. And you keep the company of Dredge, with his self-avowed IQ of 9.
Kleinman writes:
... it will make you feel so smart but they can't explain anything.
Having Dredge (IQ=9) agree with you must make you feel smart.

Come all of you cowboys all over this land,
I'll teach you the law of the Ranger's Command:
To hold a six shooter, and never to run
As long as there's bullets in both of your guns.
-- Woody Guthrie

This message is a reply to:
 Message 1909 by Kleinman, posted 11-18-2022 11:08 AM Kleinman has replied

Replies to this message:
 Message 1918 by Kleinman, posted 11-18-2022 11:55 AM ringo has replied

  
Kleinman
Member (Idle past 365 days)
Posts: 2142
From: United States
Joined: 10-06-2016


Message 1916 of 2932 (902156)
11-18-2022 11:51 AM
Reply to: Message 1913 by Taq
11-18-2022 11:27 AM


Kleinman:
The Kishony and Lenski experiments demonstrate exactly how descent with modification operates.
Taq:
The Lenski experiment had a constant environment for 10's of thousands of generations. Are you saying that a constant environment does not disqualify an experiment?

You are so stupid. The Kishony experiment works quickly because his lineages can accumulate their 1/(mutation rate) replications without having to deal with biological competition. The Lenski populations accumulate their 1/(mutation rate) replications more slowly because they have to deal with biological competition.
Kleinman:
Desai created a special environment that increases the frequencies of adaptive alleles.
Taq:
How was the Desai experiment any different than the Kishony/Lenski experiment with regard to environments that increase the frequency of adaptive alleles?

Also, the asexual and sexual populations in the Desai experiment were in the same environment. Clonal interference was only seen in the asexual population, not in the sexual population even though they were in the same environment. It wasn't the constant environment that caused the removal of clonal interference in the sexual population. It was recombination that alleviated clonal interference.

We've discussed this many, many times and you still don't get it. The only reason that Desai's population doesn't see the effect of clonal interference is that he lets his population increase the frequencies of a few adaptive alleles and then induces sexual reproduction after 90 generations of constant selection. If Desai allowed his environment to change, who knows if any alleles would have increased in frequencies and who knows what kind of recombination events would have happened. You are such a slow learner.
Kleinman:
Descent with modification depends on the number of replications a particular variant can do.
Taq:
It also depends on the existence of sexual recombination, as shown in the Desai experiment.

Why don't you do the math with a varying environment and see how much recombination helps? It certainly doesn't help HIV, weeds, and insects. Your stupid speculations don't cut it.

This message is a reply to:
 Message 1913 by Taq, posted 11-18-2022 11:27 AM Taq has replied

Replies to this message:
 Message 1920 by Taq, posted 11-18-2022 12:09 PM Kleinman has replied

  
Kleinman
Member (Idle past 365 days)
Posts: 2142
From: United States
Joined: 10-06-2016


Message 1917 of 2932 (902157)
11-18-2022 11:53 AM
Reply to: Message 1914 by Tanypteryx
11-18-2022 11:47 AM


Tanypteryx:
So still no evidence, just handwaving and blaming others for your own failures. Thanks a lot Bullshit Peddler.
Have you found any bugs that explain biological evolution? Tell us about them.

This message is a reply to:
 Message 1914 by Tanypteryx, posted 11-18-2022 11:47 AM Tanypteryx has not replied

  
Kleinman
Member (Idle past 365 days)
Posts: 2142
From: United States
Joined: 10-06-2016


Message 1918 of 2932 (902159)
11-18-2022 11:55 AM
Reply to: Message 1915 by ringo
11-18-2022 11:47 AM


Re: Kleinman does not know asexual vs sexual
Kleinman:
To you, good company doesn't understand biological evolution.
ringo:
Huh? I respect and admire biologists. You're the one who claims they don't know what they're doing.

Good for you, your friends can't explain biological evolution, the evolution of drug resistance, and why cancer treatments fail. Your friend are really smart.

This message is a reply to:
 Message 1915 by ringo, posted 11-18-2022 11:47 AM ringo has replied

Replies to this message:
 Message 1919 by ringo, posted 11-18-2022 11:58 AM Kleinman has replied

  
ringo
Member (Idle past 441 days)
Posts: 20940
From: frozen wasteland
Joined: 03-23-2005


Message 1919 of 2932 (902160)
11-18-2022 11:58 AM
Reply to: Message 1918 by Kleinman
11-18-2022 11:55 AM


Re: Kleinman does not know asexual vs sexual
Kleinman writes:
Good for you, your friends can't explain biological evolution, the evolution of drug resistance, and why cancer treatments fail.
They can explain it to everybody's satisfaction but yours.
Kleinman writes:
Your friend are really smart.
And you're not.

Come all of you cowboys all over this land,
I'll teach you the law of the Ranger's Command:
To hold a six shooter, and never to run
As long as there's bullets in both of your guns.
-- Woody Guthrie

This message is a reply to:
 Message 1918 by Kleinman, posted 11-18-2022 11:55 AM Kleinman has replied

Replies to this message:
 Message 1921 by Kleinman, posted 11-18-2022 12:11 PM ringo has replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(1)
Message 1920 of 2932 (902162)
11-18-2022 12:09 PM
Reply to: Message 1916 by Kleinman
11-18-2022 11:51 AM


Kleinman writes:
You are so stupid. The Kishony experiment works quickly because his lineages can accumulate their 1/(mutation rate) replications without having to deal with biological competition.
You didn't address what I said. Here it is again.
The Lenski experiment had a constant environment for 10's of thousands of generations. Are you saying that a constant environment does not disqualify an experiment?
As to the Kishony experiment, what would the dynamics of adaption to chloramphenicol look like if the E. coli in the experiment were undergoing sexual recombination? How would it compare to a population of asexual E. coli adapting to the same environment?
Imagine if scientists published a paper on that very experiment? Well we don't have to imagine.
quote:
From the evolution experiments in each fitness landscape, we find that increased mutation rate expedite adaptation in some environments tested, and that sexual recombination further speed up adaptive evolution in some environments. We also observe strong evidence of an in situ recombination event that help to alleviate clonal interference and generate a superior genotype in a sexual E. coli.
Sexual recombination and increased mutation rate expedite evolution of Escherichia coli in varied fitness landscapes

Look at the title of that paper. Wouldn't you know it, sexual recombination speeds up adaptation, and it does so by alleviating clonal inteference. More from the paper:
quote:
The results suggest that sexual recombination facilitates a more swift increase in resistance, probably by combining compatible determinants of CM tolerance.
CM tolerance is chloramphenicol resistance. Sexual recombination combines different beneficial mutations in different genes into the same genetic background, thereby speeding up adaptation to chloramphenicol.
The only reason that Desai's population doesn't see the effect of clonal interference is that he lets his population increase the frequencies of a few adaptive alleles and then induces sexual reproduction after 90 generations of constant selection.
Yes, it is sexual recombination that alleviates clonal interference.
If Desai allowed his environment to change, who knows if any alleles would have increased in frequencies and who knows what kind of recombination events would have happened.
Why wouldn't those same beneficial mutations increase in frequency if there was sexual recombination in every generation?
Why don't you do the math with a varying environment and see how much recombination helps?
The experiment was already run. It helps.

This message is a reply to:
 Message 1916 by Kleinman, posted 11-18-2022 11:51 AM Kleinman has replied

Replies to this message:
 Message 1924 by Kleinman, posted 11-18-2022 12:43 PM Taq has replied

  
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