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Author Topic:   Coffee House Musings on Creationist Topic Proposals
Taq
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Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


Message 1186 of 1429 (903038)
12-01-2022 10:39 AM
Reply to: Message 1185 by Dredge
12-01-2022 4:42 AM


Re: UCD evidence
Dredge writes:
More Darwinist delusion. Wake up, Dopey ... scientists didn't need the theory of UCD to determine how TRLs work in fruit flies, humans or any other mammal.
Prove it.

This message is a reply to:
 Message 1185 by Dredge, posted 12-01-2022 4:42 AM Dredge has replied

Replies to this message:
 Message 1187 by Dredge, posted 12-01-2022 11:05 AM Taq has replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(2)
Message 1188 of 1429 (903040)
12-01-2022 11:12 AM
Reply to: Message 1187 by Dredge
12-01-2022 11:05 AM


Re: UCD evidence
Dredge writes:
You want me to prove a negative?
The fact of the matter is that they used UCD to discover the role of toll-like receptors in the human genome. You asked for examples. This is one of them.
But you can't prove that it was "through common descent" that scientists determined how TLRs work.
It was because of UCD that they hypothesized toll proteins would have the same function in humans as it does in fruit flies.
quote:
Two and a half years later, the idea of innate immunity in humans and its connections to defense in invertebrates had already taken hold. At least 150 scientists gathered at a National Academy of Sciences colloquium in Irvine, Calif., entitled “Virulence and Defense in Host-Pathogen Interactions: Common Features between Plants and Animals.” At the meeting, 12 researchers specifically discussed their work on toll in flies and “toll-like receptors”—as the mammalian versions are now known—and other aspects of innate immunity. Two dozen other scientists focused on patterns common to the insect and mammalian pathogens.
By March 2001, scientists had found 10 other human toll-like receptors, including toll-like receptor 2, which Shizuo Akira, MD, and colleagues at Osaka University showed responds to a particular sequence found in bacterial DNA but not in mammalian DNA. To get an idea of how fast the field has grown since 1997, a literature search for the term “toll-like receptor” in 2022 brought up more than 56,000 abstracts.
The evolutionary connections also awed researchers, as they eventually found toll-like molecules in worms, mice, even plants. Plant geneticist Santosh Misra, PhD, and colleagues at the University of Victoria in British Columbia genetically engineered antimicrobial peptides into potatoes to get the crops to withstand fungal infection. Protective compounds produced by plants could conceivably work as new classes of antibiotics in people as well.
The History Behind The Discovery of toll-like Receptors < Yale School of Medicine

This message is a reply to:
 Message 1187 by Dredge, posted 12-01-2022 11:05 AM Dredge has replied

Replies to this message:
 Message 1189 by Theodoric, posted 12-01-2022 3:36 PM Taq has not replied
 Message 1204 by Dredge, posted 12-06-2022 7:48 AM Taq has replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(6)
Message 1191 of 1429 (903049)
12-01-2022 6:11 PM


Analogy
An analogy for this thread:
Frank: Airplanes are useless as modes of transportation.
Abe: That's not true. I flew in an airplane from Boston to Atlanta, and it worked great.
Frank: That doesn't count since you could have driven in a car from Boston to Atlanta.
Abe: But I didn't drive in a car. I flew in an airplane.
Frank: Well, you didn't have to fly, so airplanes are still useless.

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(3)
Message 1198 of 1429 (903165)
12-05-2022 1:46 PM
Reply to: Message 1193 by Dredge
12-03-2022 9:51 PM


Re: UCD evidence
Dredge writes:
That is pure speculation ... no one can possibly know "how evolution has endowed different species with similar traits".
"Denial ain't just a river in Egypt."--Mark Twain
Sorry, but refusing to accept reality is not a valid refutation. We can know, and we do know.
"we predict"? "we expect"? Is that all the author has to offer ... wishful thinking?
It's called a hypothesis, otherwise known as "doing science". Now you are rejecting science as a whole.

This message is a reply to:
 Message 1193 by Dredge, posted 12-03-2022 9:51 PM Dredge has replied

Replies to this message:
 Message 1200 by Dredge, posted 12-05-2022 7:17 PM Taq has replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(1)
Message 1207 of 1429 (903199)
12-06-2022 10:37 AM
Reply to: Message 1200 by Dredge
12-05-2022 7:17 PM


Re: UCD evidence
Dredge writes:
The discussion is not about an "hypothesis" or "doing science" ... it's about a practical use in medical science or biology for the theory of UCD.
And I have given you examples of just that.
Your response?
An "hypothesis" per se is just an idea floating around in someone's mind, not a practical use.
It is absolutely a practical use. Finding routes for research is a very, very practical application for any theory.
If the article you provided in Message 1109 describes a practical use in medical science or biology for the theory of UCD, what is it, exactly?
The practical use is in selecting animal models that will yield the best results in biomedical research.

This message is a reply to:
 Message 1200 by Dredge, posted 12-05-2022 7:17 PM Dredge has replied

Replies to this message:
 Message 1312 by Dredge, posted 12-17-2022 5:42 AM Taq has not replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(3)
Message 1208 of 1429 (903202)
12-06-2022 10:41 AM
Reply to: Message 1204 by Dredge
12-06-2022 7:48 AM


Re: UCD evidence
Dredge writes:
On the contrary, the article describes how Medzhitov noticed (from Hoffman's work) "that flies with defects in their toll genes became hypersusceptible to fungal infection."

That observation gave Medzhitov the idea that toll genes might act as a sensor, and he then applied that idea to the human immune system.

So what Medzhitov performed was simply an exercise in comparative physiology ... which doesn't require the theory of UCD.
False. Scientists apply phylogenies which are based on evolutionary histories.
Darwinist propaganda in that passage, as if none of the knowledge described could have been gained without recognizing the "evolutionary connections".
The knowledge was gained through our understanding of evolution and the evolutionary history of life. It appears my analogy was dead on:
Frank: Airplanes are useless as modes of transportation.
Abe: That's not true. I flew in an airplane from Boston to Atlanta, and it worked great.
Frank: That doesn't count since you could have driven in a car from Boston to Atlanta.
Abe: But I didn't drive in a car. I flew in an airplane.
Frank: Well, you didn't have to fly, so airplanes are still useless.

This message is a reply to:
 Message 1204 by Dredge, posted 12-06-2022 7:48 AM Dredge has replied

Replies to this message:
 Message 1209 by xongsmith, posted 12-06-2022 11:20 AM Taq has not replied
 Message 1323 by Dredge, posted 12-18-2022 9:21 AM Taq has not replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(3)
Message 1218 of 1429 (903226)
12-06-2022 12:41 PM
Reply to: Message 1214 by Dredge
12-06-2022 12:20 PM


Re: UCD evidence
Dredge writes:
as in "Golly gee whiz, since humans are mammals, maybe insulin from other mammals - such as cows and pigs - will work in humans. Let's try it." A pretty basic idea, really.
You lack the common sense to understand why there is no reason for a mammal group to even exist if separate creation is true. There is absolutely no reason why a nested hierarchy should exist within creationism.

This message is a reply to:
 Message 1214 by Dredge, posted 12-06-2022 12:20 PM Dredge has replied

Replies to this message:
 Message 1220 by Dredge, posted 12-06-2022 11:59 PM Taq has not replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(3)
Message 1233 of 1429 (903253)
12-07-2022 10:42 AM
Reply to: Message 1224 by Dredge
12-07-2022 12:44 AM


Re: UCD evidence
Dredge writes:
Your comment, although entertaining, didn't answer my question.
"Why do you need to believe that all life shares a common ancestor to examine and compare the DNA of humans and other animals?"--Dredge
Wrong question. There is no "need to believe". You either want to understand how biology or you don't. That's the choice. If you want to understand biology then evolution and UCD are the best tools for understanding biology. If you don't want to understand biology and instead protect a failing theology, then you make the arguments you are making. It's a choice, not a need.
For example, can you explain why there is more sequence conservation in exons than in introns when we align orthologous sequence between disparate species? What can we use from ID/creationism to help explain this pattern? I can't think of anything. However, this is EXACTLY the pattern of sequence conservation we would expect from evolution and UCD. Exactly.
What about the pattern of base substitutions? Can ID/creationism explain to us why we see more transitions than transversions when we compare single nucleotide polymorphisms between different species? No. Evolution and UCD can, and they allow us to understand what we are seeing in biology.
What about the pattern of shared and derived features? Can ID/creationism explain why we see a nested hierarchy instead of some other pattern? No. However, this pattern is exactly what we would expect to see if evolution and UCD are true. Those concepts allow us to understand what we are seeing in biology.
I could go on and on and on. You either want to understand biology or you want to protect a failed theology. Your choice.

This message is a reply to:
 Message 1224 by Dredge, posted 12-07-2022 12:44 AM Dredge has not replied

Replies to this message:
 Message 1235 by dwise1, posted 12-07-2022 11:41 AM Taq has replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(1)
Message 1234 of 1429 (903254)
12-07-2022 10:45 AM
Reply to: Message 1221 by Dredge
12-07-2022 12:05 AM


Re: UCD evidence
Dredge writes:
Show me a scientific paper that says animal models are used because of UCD.
I already did that.
https://www.evcforum.net/dm.php?control=msg&m=902182#m902183

This message is a reply to:
 Message 1221 by Dredge, posted 12-07-2022 12:05 AM Dredge has not replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(2)
Message 1237 of 1429 (903259)
12-07-2022 12:42 PM
Reply to: Message 1235 by dwise1
12-07-2022 11:41 AM


Re: UCD evidence
dwise1 writes:
One of the funniest things about "creation science" is how much effort leading creationists have to put into explaining away why the evidence looks for all the world like evolution.
That comes from their raison d'etre for participating in these discussions. Are ID/creationists interested in actually figuring out why we see what we do? No. They are here to protect their beliefs. ID/creationists aren't interested in explanations. They are interested in beliefs. Science, on the other hand, is all about explanations, beliefs be damned.
This is why you see people like Dredge who use phrases like "need to believe". That's just not how it works. It is projection on the part of ID/creationists. As is true of many other areas of life, what people accuse others of is often a strong clue as to what those accusers are actually doing themselves. ID/creationists have a dogmatic belief that must be adhered to, so they assume it is the same for scientists. They never stop and think that scientists follow the evidence without reference to beliefs. Instead, we see ID/creationists labelling theories with "-isms" while calling them religions. Why? They are trying to level the playing field, and/or battling their own cognitive dissonance which is often the source of projection.
For Dredge, UCD has to be a belief because his worldview just can't cope with UCD being an evidenced based conclusion.

This message is a reply to:
 Message 1235 by dwise1, posted 12-07-2022 11:41 AM dwise1 has not replied

Replies to this message:
 Message 1242 by Phat, posted 12-07-2022 1:32 PM Taq has not replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(2)
Message 1240 of 1429 (903264)
12-07-2022 1:25 PM
Reply to: Message 1238 by Phat
12-07-2022 1:18 PM


Re: UCD evidence
Phat writes:
This sounded so outlandish that I had to investigate.
All life shares a common ancestor. If you pick any two species you can trace their family tree back until you arrive at that shared ancestor. The shared ancestor between potatoes and humans, or rather animals and plants, would be a simpler single celled eukaryote, something along the lines of modern protists. The shared ancestor would be neither a potato nor a human.

This message is a reply to:
 Message 1238 by Phat, posted 12-07-2022 1:18 PM Phat has not replied

Replies to this message:
 Message 1244 by Dredge, posted 12-07-2022 7:40 PM Taq has replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(4)
Message 1241 of 1429 (903265)
12-07-2022 1:26 PM
Reply to: Message 1239 by Dredge
12-07-2022 1:23 PM


Dredge writes:
Those researchers wouldn't know ... they're just guessing. Their proposal can't be tested and is therefore worthless as science.
It can be tested by measuring phylogenetic signal in shared DNA sequences. The fact that you have to pretend that this evidence doesn't exist says quite a lot.

This message is a reply to:
 Message 1239 by Dredge, posted 12-07-2022 1:23 PM Dredge has replied

Replies to this message:
 Message 1257 by Dredge, posted 12-08-2022 9:09 PM Taq has replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(5)
Message 1256 of 1429 (903313)
12-08-2022 11:35 AM
Reply to: Message 1244 by Dredge
12-07-2022 7:40 PM


Re: UCD evidence
Dredge writes:
Hilarious. It's amazing how many people believe that Darwinoid superstition ... an atheist fairy tale foisted on the gullible masses by atheist scientists.
Anyone who reads this thread will see that all you have is mockery, and a complete inability to address the evidence that has been presented.

This message is a reply to:
 Message 1244 by Dredge, posted 12-07-2022 7:40 PM Dredge has not replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(4)
Message 1258 of 1429 (903383)
12-09-2022 10:56 AM
Reply to: Message 1257 by Dredge
12-08-2022 9:09 PM


Dredge writes:
Anyone who thinks they know how "early life" evolved Message 1133 is delusional ... or worse.

Darwinoid scientists are amongst the most egregious bs-artists and con-men on the planet.
So you can't address the evidence we are presenting?

This message is a reply to:
 Message 1257 by Dredge, posted 12-08-2022 9:09 PM Dredge has not replied

  
Taq
Member
Posts: 10085
Joined: 03-06-2009
Member Rating: 5.1


(2)
Message 1281 of 1429 (903578)
12-13-2022 12:30 PM
Reply to: Message 1268 by Dredge
12-10-2022 11:37 PM


Re: UCD evidence
Dredge writes:
You think me asking for a practical use for UCD in medical science or applied biology is the same as asking for evidence of UCD itself Message 1152.
Ignoring the evidence you asked for is a classic creationist move.

This message is a reply to:
 Message 1268 by Dredge, posted 12-10-2022 11:37 PM Dredge has not replied

  
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