Interesting articles, thank you. So given that you are presenting these articles as reliable sources, why should we not accept their further information on the differential effects of population size on deleterious mutation accumulation?
(Although, I note, neither of those articles supports your assertion about build up of genetic entropy)
Becasue the size of the population is one of the factors that determines how much mutations will accumulate. If you do not know the initial size, than you also do not know how much mutations will accumulate.
We can still know how many will accumulate in a single genetic line (because
E. coli is asexual), that number is at least 7000 - more than one mutation per gene. Why aren't they suffering huge consequences from this problem?
Edited by Mr Jack, : No reason given.