quote:
If one sits on a hill above the factory and watches raw materials go in one side and cars come out the other, one can try to figure out what is going on inside. On the other hand, if we had some way of detecting what is going on inside the factory, perhaps with a very sensitive magnetometer which could show us where the steel goes, we could begin to trace the fabrication paths in the factory and begin to understand how autos are made
Sitting on the hill is the behavioral approach. We place subjects in a situation, watch their behavior and try figure out why they do what the do.
On the other hand, the sensitive magnetometer is analogous to FMRI. Using this technique, we can match our behavioral observations with the map of brain activity provided by FMRI, which shows which area(s) of the brain is/are active when the behavior occurs and begin to learn in detail how the brain works.
You'd think that would be how it works, wouldn't you?
Just knowing that area X of the brain is active during task Z doesn't tell you anything, really, except in a very broad sense, like a surgeon not wanting to muck up the part of the brain that deals with speech, for instance.
If you want to map functions to areas, you first have to know what those functions are through behavioral research.
There are times that behavior may not change but activity in the brain might/does, (like the same task performed by young and old subjects utilize different brain areas) which is a concept that my husband thinks is not fully appreciated by many in the field. This is a place where FMRI would be valuable on its own.
Right now, however, the biggest benefit of FMRI is that it is an additional convergent line of evidence for behavioral research. Indeed, one emergent problem with the attraction many have to doing FMRI work is that they do not have a good grounding in the behavioral research. The result is that they cannot properly interpret the brain activity because they don't understand what is required at a cognitive level to do a task.
Jim tells me that this problem is getting better nowadays, mainly because more behavioral researchers are getting into FMRI work. MR machines used to be available pretty much only to MD's, and a lot of that initial research was pretty poor quality because MD's don't generally have the background that allows them to understand congnition.
This message has been edited by schrafinator, 01-10-2005 11:05 AM