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Author Topic:   COVID vaccine works - we're saved!
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


(1)
Message 668 of 1110 (909858)
04-12-2023 8:41 AM
Reply to: Message 663 by Kleinman
04-12-2023 8:04 AM


Re: The Right to Spread Disease
Kleinman writes:
There is something else that you don't seem to understand when it comes to influenza and many other infectious diseases. In the early stages (prodrome), the patient may have minimal or no symptoms but still be capable of spreading the disease. This is why it is so difficult to stop the spread of diseases like influenza. Some people may be totally asymptomatic through the entire course of a disease, yet be spreading the disease to others unknowingly.
I think everyone here understands the "contagious before symptoms" issue. Covid provided an excellent example. Why do you think anyone here doesn't understand this?
In the case of covid we dealt with this by asking people who learned that they'd been exposed to covid to isolate for while, I think a week or so. Last year this happened to me and my wife several times.
If it makes you feel better to wear a mask, go for it. Wear a hazmat suit if it makes you feel safe. But, I don't think these things are based on understanding, they are based on fear.
Research indicates that masking has strong efficacy, but their performance in real life is tempered by the large number of people who don't mask properly. The ways masking can go wrong that I can think of at the moment:
  • Wearing a cloth mask
  • Wearing a surgical mask instead of an N95
  • Wearing the same mask many times
  • Not bending the little metal strip around the nose (surgical mask)
  • Wearing the mask upside down so that the little metal strip is on the bottom
  • Wearing the mask below the nose
  • Wearing the mask on the tip of the nose
  • Permitting large gaps on the sides
Your personal example of working in a clinical setting for 30 years and never catching influenza is anecdotal and not epidemiological. You're like the smoker who says, "I've smoked all my life and never been sick a day." Yes, that happens. It's statistical. Single examples tell us nothing.
If you have some useful information to share I wish you'd just do that instead alternating questions with taunts and insults. How about just be a decent person.
--Percy

This message is a reply to:
 Message 663 by Kleinman, posted 04-12-2023 8:04 AM Kleinman has replied

Replies to this message:
 Message 670 by Kleinman, posted 04-12-2023 8:59 AM Percy has replied
 Message 672 by Theodoric, posted 04-12-2023 9:03 AM Percy has seen this message but not replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 673 of 1110 (909863)
04-12-2023 9:04 AM
Reply to: Message 667 by Kleinman
04-12-2023 8:41 AM


Kleinman writes:
Stop whining Percy. Are you so fragile you can't take a little taunt?
Do you know so little that you're forced to fill your posts with taunts rather than information and discussion? If you're trying to be obnoxious and unlikeable you're doing a great job.
I think that people that do things intentionally to spread an infectious disease should be thrown in the slammer.
As mentioned a couple times previously, in California this approach had the unintended consequence of not improving the HIV infection rate while criminalizing a disease. They're currently taking a "middle ground" approach.
If someone is known to have an infectious disease and is doing something unknowingly to increase the chance of the spread of the disease, it is ok for authorities to do something to stop that person's activity.
Sure, in the interests of public health.
If the person still does that behavior, then, throw 'em into the slammer.
This would expose prison populations to contagions. Legally enforced isolation and treatment seems preferred.
But all of this will have minimal effect on the spread of infectious disease.
Since intentional spread of contagion is rare, I agree that in the larger scope of things that the impact is not large. A larger impact might be present in that legal consequences might convince people of the serious consequences of disease spread.
And to shut down an economy is the worst thing that you can do.
Which is worse, temporarily shutting down portions of the economy that contribute most to spread (crowded indoor venues like restaurants, bars, concert halls, etc.) or allowing that spread at the cost of greater illness and death.
.3% of the US population died of covid. 5% still suffers from long covid. Where do you draw the line? If shutting down all bars and restaurants had reduced the death rate from, just say for example, .4% to the actual .3%, would that have been worth it? I certainly don't know the answer of how to balance life against money.
--Percy

This message is a reply to:
 Message 667 by Kleinman, posted 04-12-2023 8:41 AM Kleinman has replied

Replies to this message:
 Message 675 by Kleinman, posted 04-12-2023 9:13 AM Percy has replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 678 of 1110 (909868)
04-12-2023 9:20 AM
Reply to: Message 669 by Kleinman
04-12-2023 8:47 AM


Re: The Right to Spread Disease
Kleinman writes:
Where do you want me to start? Do you want me to explain again how Haldane's frequency equation is simply a conservation of energy equation? The last time I explained that to you, you didn't seem too happy to learn something new. So, tell me where you want me to start.
I think you already gave us a clear picture of your ability to explain Haldane's stuff back in the Rebuttal To Creationists - "Since We Can't Directly Observe Evolution..." thread. In this thread you've been talking about drug resistance evolution and failing cancer treatments, so it might be best to stick to that.
--Percy

This message is a reply to:
 Message 669 by Kleinman, posted 04-12-2023 8:47 AM Kleinman has replied

Replies to this message:
 Message 683 by Kleinman, posted 04-12-2023 9:37 AM Percy has replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


(1)
Message 680 of 1110 (909870)
04-12-2023 9:27 AM
Reply to: Message 670 by Kleinman
04-12-2023 8:59 AM


Re: The Right to Spread Disease
Kleinman writes:
You are confused Percy, it is not just my personal experience, I know many physicians and healthcare personnel.
This is a perfect example of the anecdotal.
There is not a wave of disease hitting these people despite their close contact with people with infectious diseases.
There's an influenza wave nearly every winter.
The vast majority of these physicians and healthcare personnel did not wear masks until the past couple of years because of this so-called research.
When the possibility of respiratory transmission exists, research shows that masking is prudent.
The red states are full of anecdotal stories about how covid measures don't help. The red states also tend to have the highest covid case and death rates. Worst states in the country for covid right now? Montana and Texas.
--Percy

This message is a reply to:
 Message 670 by Kleinman, posted 04-12-2023 8:59 AM Kleinman has replied

Replies to this message:
 Message 685 by Kleinman, posted 04-12-2023 9:49 AM Percy has replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 682 of 1110 (909872)
04-12-2023 9:36 AM
Reply to: Message 675 by Kleinman
04-12-2023 9:13 AM


Kleinman writes:
Just wait until food production is disrupted so that malnourishment becomes widespread. Then you will really have some statistics on death due to infectious diseases to quote.
This makes no sense. Shutting down places where people congregate like bars, restaurants and concert halls wouldn't affect food production, and no one ever proposed shutting down farms, slaughter houses or food production lines.
The question you didn't address was how you balance life against money.
--Percy

This message is a reply to:
 Message 675 by Kleinman, posted 04-12-2023 9:13 AM Kleinman has replied

Replies to this message:
 Message 684 by Kleinman, posted 04-12-2023 9:43 AM Percy has replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


(1)
Message 686 of 1110 (909876)
04-12-2023 9:57 AM
Reply to: Message 683 by Kleinman
04-12-2023 9:37 AM


Re: The Right to Spread Disease
Kleinman writes:
Drug resistance and cancer treatment failure are due to the evolutionary process of "descent with modification and adaptation". This is a stochastic process, that is, randomly occurring mutations can alter the target sites for these drugs (selection pressures) used to kill or impair the replication of these disease-causing replicating agents.

If you understand this principle, I can go on and explain how these agents accumulate their adaptive mutations. If you have any questions, I'll try an answer them.
Concerning drug resistance, I think everyone here understands evolution, adaptation and descent with modification.
Concerning how that's a factor in "cancer treatment failure," it might help if you provided an example of the kind of cancer treatments you're talking about. Probably most people's general knowledge in this area is that medicine has impressively improved its record of success in treating cancer over the past couple decades.
--Percy

This message is a reply to:
 Message 683 by Kleinman, posted 04-12-2023 9:37 AM Kleinman has replied

Replies to this message:
 Message 689 by Kleinman, posted 04-12-2023 10:14 AM Percy has replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 688 of 1110 (909878)
04-12-2023 10:10 AM
Reply to: Message 684 by Kleinman
04-12-2023 9:43 AM


Kleinman writes:
We are already seeing signs of food production disruption, you can see it in your grocery bill. Must you see empty food shelves before you realize that food production is being disrupted?
But covid shutdown rules only affected places where people congregate, not food production farms or facilities. How are covid policies interfering with food production? The biggest factors I see behind increasing food prices are droughts out west, supply chain problems, labor shortages, energy prices and the Ukraine war.
--Percy

This message is a reply to:
 Message 684 by Kleinman, posted 04-12-2023 9:43 AM Kleinman has replied

Replies to this message:
 Message 691 by Kleinman, posted 04-12-2023 10:27 AM Percy has replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 690 of 1110 (909881)
04-12-2023 10:20 AM
Reply to: Message 685 by Kleinman
04-12-2023 9:49 AM


Re: The Right to Spread Disease
Kleinman writes:
So what? Are you claiming that physicians and healthcare personnel are contracting influenza at a higher incidence then the general population?
By "these people" I guess you meant physicians, not the people seeing physicians. I have no idea of physician incidence rates, but aren't people in the medical field more likely than most to get the annual influenza vaccine? If that's the case then their influenza rate could well be lower than the general population, though you also have to take into account their likely higher exposure rate, so I don't know how those two effects would balance out.
--Percy

This message is a reply to:
 Message 685 by Kleinman, posted 04-12-2023 9:49 AM Kleinman has replied

Replies to this message:
 Message 692 by Kleinman, posted 04-12-2023 10:31 AM Percy has replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 693 of 1110 (909884)
04-12-2023 11:11 AM
Reply to: Message 689 by Kleinman
04-12-2023 10:14 AM


Re: The Right to Spread Disease
Keinman writes:
Who here understands the mathematical behavior of descent with modification and adaptation? Taq understood that I did the math correctly for asexual replications but claimed that recombination causes a significant difference in the process. He uses a constant environment single selection pressure environment to argue his point. He refused to acknowledge what happens in a multiple-selection pressure environment.

With regards to cancer treatment failure, it is targeted cancer therapies. Single-drug targeted cancer therapy faces the same problem that single-drug antimicrobial therapy faces. If the target site mutates such that the agent that is being used cannot bind (react correctly) with that site, that variant cell will have some resistance to that agent. The problem that oncologists face is finding alternate targets that the normal host cells don't have. This is a much more difficult task since cancer cells are variants of normal host cells. That is not the case when looking for targets in microbes.
Sure, but how does that tie in to HIV and all those questions you asked regarding locking up contagious people, which is where you started. I thought your evolution/cancer points would tie back to that somehow. Did you change subjects?
--Percy

This message is a reply to:
 Message 689 by Kleinman, posted 04-12-2023 10:14 AM Kleinman has replied

Replies to this message:
 Message 696 by Kleinman, posted 04-12-2023 11:41 AM Percy has replied
 Message 700 by Theodoric, posted 04-12-2023 11:54 AM Percy has seen this message but not replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 694 of 1110 (909885)
04-12-2023 11:28 AM
Reply to: Message 691 by Kleinman
04-12-2023 10:27 AM


Kleinman writes:
But I think your claim that shutting down one part of the economy has no effect on another part of the economy is not correct.
Your claim that I claimed that is incorrect. Sure, everything's interconnected, but covid shutdowns are not one of the significant contributors to increased food costs. Drought, labor shortages, supply chain issues and the Ukraine war are the significant contributors, just as I said.
It just demonstrates that the government is not well prepared to deal with droughts, supply chain problems, labor shortages, energy prices, and war.
Which still doesn't support the case that covid shutdowns are a significant factor in food production.
Shutting down any portion of the economy under these circumstances will only stress the system more.
Sure, everything's interconnected. This still doesn't make the case that covid shutdowns are a significant impactor on food production.
One of the results of all these policies is an increased cost in food production, an early sign of disruption of food production.
Again, still not a case that covid shutdowns are a significant impactor on food production.
I'm not arguing for or against shutdowns, only saying that you can't blame declines in food production on covid shutdowns to any meaningful extent.
--Percy

This message is a reply to:
 Message 691 by Kleinman, posted 04-12-2023 10:27 AM Kleinman has replied

Replies to this message:
 Message 697 by Kleinman, posted 04-12-2023 11:42 AM Percy has seen this message but not replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 695 of 1110 (909886)
04-12-2023 11:33 AM
Reply to: Message 692 by Kleinman
04-12-2023 10:31 AM


Re: The Right to Spread Disease
Kleinman writes:
You posted my quote. Where did I write "these people"?
From your Message 670:
Kleinman in Message 670:
There is not a wave of disease hitting these people despite their close contact with people with infectious diseases.
But as I said, I see now that you meant physicians when you said "these people."
--Percy

This message is a reply to:
 Message 692 by Kleinman, posted 04-12-2023 10:31 AM Kleinman has replied

Replies to this message:
 Message 698 by Kleinman, posted 04-12-2023 11:47 AM Percy has seen this message but not replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


(1)
Message 703 of 1110 (909895)
04-12-2023 1:56 PM
Reply to: Message 696 by Kleinman
04-12-2023 11:41 AM


Re: The Right to Spread Disease
Kleinman writes:
The inability of HIV to evolve efficiently to 3-drug therapy should be a lesson to people that think that reptiles evolve into birds and fish evolve into mammals.

And I only advocate that biologists and atheists be locked up. I look forward to your response to this.
This is a Coffee House thread on Covid. Your Rebuttal To Creationists - "Since We Can't Directly Observe Evolution..." thread over in the Biological Evolution forum where you last discussed this topic is probably more appropriate. It's still open. Or you could propose a new thread.
--Percy

This message is a reply to:
 Message 696 by Kleinman, posted 04-12-2023 11:41 AM Kleinman has replied

Replies to this message:
 Message 704 by Kleinman, posted 04-12-2023 2:05 PM Percy has replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


Message 705 of 1110 (909897)
04-12-2023 4:33 PM
Reply to: Message 704 by Kleinman
04-12-2023 2:05 PM


Re: The Right to Spread Disease
Kleinman writes:
The same principles of the suppression of the evolution of drug resistance of HIV to 3-drug therapy apply to Covid, Influenza, or any kind of replicator that you can think of.
If you still want to discuss this then the appropriate thread is the one where you were originally discussing it. Please don't turn this thread into another discussion of the same thing.
--Percy

This message is a reply to:
 Message 704 by Kleinman, posted 04-12-2023 2:05 PM Kleinman has replied

Replies to this message:
 Message 706 by Kleinman, posted 04-12-2023 5:02 PM Percy has replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


(1)
Message 707 of 1110 (909911)
04-13-2023 7:20 AM
Reply to: Message 706 by Kleinman
04-12-2023 5:02 PM


Re: The Right to Spread Disease
I'll recuse myself from discussion for the requisite two days then assume moderatorship of this thread.
--Percy

This message is a reply to:
 Message 706 by Kleinman, posted 04-12-2023 5:02 PM Kleinman has replied

Replies to this message:
 Message 708 by Kleinman, posted 04-13-2023 8:21 AM Percy has seen this message but not replied

  
Percy
Member
Posts: 22505
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.4


(1)
Message 714 of 1110 (909920)
04-13-2023 9:26 AM
Reply to: Message 709 by Tangle
04-13-2023 8:28 AM


Re: The Right to Spread Disease
Tangle writes:
A vaccine doesn't protect you from getting infected with the given disease or necessarily prevent the spread of the disease.
And there it is. Full on stupid.
This seems relevant to covid, so I'll comment.
A vaccine ramps up the immune system to target a specific type of pathogen. The immune system is a complex system that can maintain, to varying extents dependent upon pathogen, a history of past infections.
Because the cells of the immune system exist only within the body, they cannot mount a defense against a pathogen until it enters the body and is detected by the immune system. In other words, the immune system cannot begin to do it's job until you're already infected.
What usually happens with a successfully vaccinated person is that the pathogen enters the body and is detected by the immune system, which then fights it off. Oftentimes the person does not even know he was ever infected.
Whether a pathogen spreads through a population is dependent upon many factors, including existing immunity (which doesn't really mean immunity in this context), the vaccination rate, the effectiveness of the vaccine, the effectiveness of its administration, and individual response to the vaccine.
This is all information that has been presented in this thread before. See Message 254 for a better explanation of immunity and how the immune system works.
--Percy

This message is a reply to:
 Message 709 by Tangle, posted 04-13-2023 8:28 AM Tangle has not replied

Replies to this message:
 Message 715 by Kleinman, posted 04-13-2023 9:56 AM Percy has replied

  
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