COVID vaccine works - we're saved!

She is a primary care provider. That is outside of her purview. Can you explain the most effective way to treat chronic pain patients? Do you know the processes to set up and maintain an integrated health system in order to provide services across the whole spectrum of patients in a urban/rural area? Are you aware of the medical issues and procedures involved in caring for transsexual patients?
She can and she isn't are narcissistic ass out about it. Also. She is willing and able to explain these to interested people.

Well we got through COVID without it happening. I am sure even better plans are being worked on for the next pandemic.

I think you already gave us a clear picture of your ability to explain Haldane's stuff back in the Rebuttal To Creationists - "Since We Can't Directly Observe Evolution..." thread. In this thread you've been talking about drug resistance evolution and failing cancer treatments, so it might be best to stick to that.--Percy

Theodoric:

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She is a primary care provider. That is outside of her purview. Can you explain the most effective way to treat chronic pain patients? Do you know the processes to set up and maintain an integrated health system in order to provide services across the whole spectrum of patients in a urban/rural area? Are you aware of the medical issues and procedures involved in caring for transsexual patients?
She can and she isn't are narcissistic ass out about it. Also. She is willing and able to explain these to interested people.

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Oh, she is one of those primary care physicians that treat infectious diseases but don't know how drug resistance evolves. She must have been trained by biologists because they don't know how drug resistance evolves either.

This is a perfect example of the anecdotal. There's an influenza wave nearly every winter. When the possibility of respiratory transmission exists, research shows that masking is prudent.The red states are full of anecdotal stories about how covid measures don't help. The red states also tend to have the highest covid case and death rates. Worst states in the country for covid right now? Montana and Texas.--Percy

She follows evidence based medicine and it sure looks like you are resorting to a strawman again, with a gish gallop thrown in too.

This makes no sense. Shutting down places where people congregate like bars, restaurants and concert halls wouldn't affect food production, and no one ever proposed shutting down farms, slaughter houses or food production lines.The question you didn't address was how you balance life against money.--Percy

Kleinman:

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Where do you want me to start? Do you want me to explain again how Haldane's frequency equation is simply a conservation of energy equation? The last time I explained that to you, you didn't seem too happy to learn something new. So, tell me where you want me to start.

Percy:

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I think you already gave us a clear picture of your ability to explain Haldane's stuff back in the Rebuttal To Creationists - "Since We Can't Directly Observe Evolution..." thread. In this thread you've been talking about drug resistance evolution and failing cancer treatments, so it might be best to stick to that.

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Ok, let's start there.Drug resistance and cancer treatment failure are due to the evolutionary process of "descent with modification and adaptation". This is a stochastic process, that is, randomly occurring mutations can alter the target sites for these drugs (selection pressures) used to kill or impair the replication of these disease-causing replicating agents.If you understand this principle, I can go on and explain how these agents accumulate their adaptive mutations. If you have any questions, I'll try an answer them.

Kleinman:

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Just wait until food production is disrupted so that malnourishment becomes widespread. Then you will really have some statistics on death due to infectious diseases to quote.

Percy:

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This makes no sense. Shutting down places where people congregate like bars, restaurants and concert halls wouldn't affect food production, and no one ever proposed shutting down farms, slaughter houses or food production lines.
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The question you didn't address was how you balance life against money.

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We are already seeing signs of food production disruption, you can see it in your grocery bill. Must you see empty food shelves before you realize that food production is being disrupted?

Kleinman:

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You are confused Percy, it is not just my personal experience, I know many physicians and healthcare personnel.

Percy:

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This is a perfect example of the anecdotal.

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And

Kleinman:

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There is not a wave of disease hitting these people despite their close contact with people with infectious diseases.

Percy:

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There's an influenza wave nearly every winter.

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So what? Are you claiming that physicians and healthcare personnel are contracting influenza at a higher incidence then the general population?

Concerning drug resistance, I think everyone here understands evolution, adaptation and descent with modification.Concerning how that's a factor in "cancer treatment failure," it might help if you provided an example of the kind of cancer treatments you're talking about. Probably most people's general knowledge in this area is that medicine has impressively improved its record of success in treating cancer over the past couple decades.--Percy

Theodoric:

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She follows evidence based medicine and it sure looks like you are resorting to a strawman again, with a gish gallop thrown in too.

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Her evidence doesn't tell her how drug resistance evolves and why cancer treatments fail. Tell her to look harder, especially if she wants to treat infectious diseases.

But covid shutdown rules only affected places where people congregate, not food production farms or facilities. How are covid policies interfering with food production? The biggest factors I see behind increasing food prices are droughts out west, supply chain problems, labor shortages, energy prices and the Ukraine war.--Percy

Kleinman:

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Drug resistance and cancer treatment failure are due to the evolutionary process of "descent with modification and adaptation". This is a stochastic process, that is, randomly occurring mutations can alter the target sites for these drugs (selection pressures) used to kill or impair the replication of these disease-causing replicating agents.
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If you understand this principle, I can go on and explain how these agents accumulate their adaptive mutations. If you have any questions, I'll try an answer them.

Percy:

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Concerning drug resistance, I think everyone here understands evolution, adaptation and descent with modification.
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Concerning how that's a factor in "cancer treatment failure," it might help if you provided an example of the kind of cancer treatments you're talking about. Probably most people's general knowledge in this area is that medicine has impressively improved its record of success in treating cancer over the past couple decades.

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Who here understands the mathematical behavior of descent with modification and adaptation? Taq understood that I did the math correctly for asexual replications but claimed that recombination causes a significant difference in the process. He uses a constant environment single selection pressure environment to argue his point. He refused to acknowledge what happens in a multiple-selection pressure environment.With regards to cancer treatment failure, it is targeted cancer therapies. Single-drug targeted cancer therapy faces the same problem that single-drug antimicrobial therapy faces. If the target site mutates such that the agent that is being used cannot bind (react correctly) with that site, that variant cell will have some resistance to that agent. The problem that oncologists face is finding alternate targets that the normal host cells don't have. This is a much more difficult task since cancer cells are variants of normal host cells. That is not the case when looking for targets in microbes.

By "these people" I guess you meant physicians, not the people seeing physicians. I have no idea of physician incidence rates, but aren't people in the medical field more likely than most to get the annual influenza vaccine? If that's the case then their influenza rate could well be lower than the general population, though you also have to take into account their likely higher exposure rate, so I don't know how those two effects would balance out.--Percy