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Author Topic:   Age and Down Syndrome?
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 43 of 76 (714053)
12-19-2013 1:13 PM
Reply to: Message 42 by NoNukes
12-19-2013 1:05 PM


For the last time, my entire position is just that damage is not a good word to use in this context. Damage is simply not the correct terminology! That's all I'm saying, for God's sake!

This message is a reply to:
 Message 42 by NoNukes, posted 12-19-2013 1:05 PM NoNukes has replied

Replies to this message:
 Message 47 by NoNukes, posted 12-19-2013 4:41 PM PlanManStan has replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 45 of 76 (714078)
12-19-2013 3:37 PM
Reply to: Message 44 by New Cat's Eye
12-19-2013 2:13 PM


"Look it up" isn't synonymous with "Google it".
And is it? Is "normal" defined as what the gene did before the mutation? Isn't that gene, then, abnormal based on what it is a mutation of?
It isn't what it was before, but is that necessarily "damage"? I understand where you are coming from and don't doubt your knowledge, I'm just saying that damage is a poor word to use, because it implies certain things, like tampering. The way "damage" is usually used, it implies someone tampered with something and caused it harm.

This message is a reply to:
 Message 44 by New Cat's Eye, posted 12-19-2013 2:13 PM New Cat's Eye has replied

Replies to this message:
 Message 46 by New Cat's Eye, posted 12-19-2013 4:18 PM PlanManStan has replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 48 of 76 (714093)
12-19-2013 4:57 PM
Reply to: Message 46 by New Cat's Eye
12-19-2013 4:18 PM


I have no idea how to use the quote function. No one has told me. Remember, this is my 6th day on this site.
What do you mean by "when a gene gets fixated"?
I see your point, and there's nothing to argue about, because we are agreeing here that damage is a sloppy term

This message is a reply to:
 Message 46 by New Cat's Eye, posted 12-19-2013 4:18 PM New Cat's Eye has replied

Replies to this message:
 Message 50 by New Cat's Eye, posted 12-19-2013 5:11 PM PlanManStan has not replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 49 of 76 (714094)
12-19-2013 4:59 PM
Reply to: Message 47 by NoNukes
12-19-2013 4:41 PM


Okay, let's say there's a gene for, I don't know, having your legs be 45 inches. Now, the gene mutates and legs are only 43 inches. Is that damage? No, it is change. All I'm saying is that change is a better term here, if we want to be nit-picky. This is hardly about Faith anymore, is he even here still?

This message is a reply to:
 Message 47 by NoNukes, posted 12-19-2013 4:41 PM NoNukes has replied

Replies to this message:
 Message 51 by NoNukes, posted 12-20-2013 7:58 AM PlanManStan has replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 52 of 76 (714152)
12-20-2013 9:48 AM
Reply to: Message 51 by NoNukes
12-20-2013 7:58 AM


So because everyone else would call it damage, that makes it more correct?
Let's imagine a mutation that produces an inheritable change where the organism has no legs at all. Or where the animal is born with a spinal cord that won't transmit signals to the legs.
I would definitely call that detrimental, I just wouldn't say the word damage.

This message is a reply to:
 Message 51 by NoNukes, posted 12-20-2013 7:58 AM NoNukes has replied

Replies to this message:
 Message 53 by 1.61803, posted 12-20-2013 11:02 AM PlanManStan has not replied
 Message 54 by NoNukes, posted 12-20-2013 11:49 AM PlanManStan has replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 55 of 76 (714176)
12-20-2013 11:59 AM
Reply to: Message 54 by NoNukes
12-20-2013 11:49 AM


I'm not trying to, like, troll. I was making an argument for why using the word "damage" is not correct. Regardless of what the word actually means, it is how it is commonly used. For example, we use the word "peruse" to mean "skim over quickly" commonly, but it actually means to read something, usually quite thorough and careful way. Similarly, we use damage in a sense that it was tampered with by an outside force (like a small child, or a hurricane), even though it may mean something else. Do you see my point?

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 Message 54 by NoNukes, posted 12-20-2013 11:49 AM NoNukes has not replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 60 of 76 (714240)
12-20-2013 7:02 PM
Reply to: Message 59 by NoNukes
12-20-2013 6:59 PM


Here we have one person who claims that all mutations are damage and another who answers by saying no mutations cause damage. Both claims are wrong.
Who said that, and when? Please, go on and quote it. As I have said, "damage" in its most common usage implies tampering, and as far as I know, there isn't some little man in your DNA tampering with your genetic information.

This message is a reply to:
 Message 59 by NoNukes, posted 12-20-2013 6:59 PM NoNukes has replied

Replies to this message:
 Message 61 by NoNukes, posted 12-20-2013 7:28 PM PlanManStan has replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 65 of 76 (714254)
12-20-2013 9:04 PM
Reply to: Message 61 by NoNukes
12-20-2013 7:28 PM


Re: Stop asserting and provide an argument.
Yes you did say that and it's wrong. In fact you've already been provided with examples of damage resulting without the action of a human agent. Does the term 'brain damage' imply that someone hit you with a hammer? Does UV radiation not cause damage to your skin?
I never said it had to be a human agent. Where'd that idea come from? I was simply reminding you that we had covered this ground before. And please quote me freely, because you seem to be lacking that. I mean, the least you could do is give examples!
Anyway, all this argument is is terminology, and I'm frankly bored with it, so I probably won't respond much more, but just to clear this up: the way we usually use the term "damage" (as a verb, of course) implies a subject (e.g. I damaged that, the plane damaged the building, etc.). That isn't the case with genomes. There is no "I" damaging the genes and no plane crashing into them.
Does the term 'brain damage' imply that someone hit you with a hammer?
I never said it had to be human!
And I am fairly certain that UV radiation damages your skin CELLS. We are strictly talking about the genetic information.

This message is a reply to:
 Message 61 by NoNukes, posted 12-20-2013 7:28 PM NoNukes has replied

Replies to this message:
 Message 66 by NoNukes, posted 12-20-2013 11:35 PM PlanManStan has replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 67 of 76 (714269)
12-20-2013 11:45 PM
Reply to: Message 66 by NoNukes
12-20-2013 11:35 PM


Re: Stop asserting and provide an argument.
I've provided an argument, and that argument was "using 'damage' to apply to genetic mutations is not a great thing to do, because 'damage' has connotations that shouldn't be applied". Somehow its been blown into this whole new thing, though. You still can't even tell me how damage is an okay word to use, other than the textbook definition which, if we know anything about language and humanity, is pointless because there are many words which we use differently than what the dictionary says.

This message is a reply to:
 Message 66 by NoNukes, posted 12-20-2013 11:35 PM NoNukes has replied

Replies to this message:
 Message 68 by NoNukes, posted 12-21-2013 12:35 AM PlanManStan has replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 69 of 76 (714272)
12-21-2013 12:47 AM
Reply to: Message 68 by NoNukes
12-21-2013 12:35 AM


Re: Stop asserting and provide an argument.
First, that wasn't your argument. It's a twisting of what AZPaul said.
No, no, I'm pretty sure I said this:
For the last time, my entire position is just that damage is not a good word to use in this context. Damage is simply not the correct terminology! That's all I'm saying, for God's sake!
many mutations are caused by the environment.
Where is the study saying this? Who has ever asserted this? Where is your evidence, your statistics?
I'm starting to think this is really stupid. We're arguing over a word that isn't even used in this thread's topic.

This message is a reply to:
 Message 68 by NoNukes, posted 12-21-2013 12:35 AM NoNukes has seen this message but not replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 70 of 76 (714273)
12-21-2013 12:51 AM
Reply to: Message 68 by NoNukes
12-21-2013 12:35 AM


Re: Stop asserting and provide an argument.
I actually misread your post. You said that "many" mutations were caused by the enviornment, not "most". That's my bad. I still have a problem with this, however:
It may well be that the majority of mutations, beneficial, neutral, or deleterious, are not spontaneous

This message is a reply to:
 Message 68 by NoNukes, posted 12-21-2013 12:35 AM NoNukes has replied

Replies to this message:
 Message 71 by NoNukes, posted 12-21-2013 1:06 AM PlanManStan has replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 72 of 76 (714276)
12-21-2013 1:08 AM
Reply to: Message 71 by NoNukes
12-21-2013 1:06 AM


Re: Stop asserting and provide an argument.
Are you prepared to argue against it or otherwise demonstrate that it is wrong? Or is it that you just don't like it?
I don't have to argue against it. You have to prove it to me. You made the claim, now back it up. I'm open to having my mind changed.
quote:
claims made without evidence can be dismissed without evidence
-Hitchens (paraphrased)

This message is a reply to:
 Message 71 by NoNukes, posted 12-21-2013 1:06 AM NoNukes has replied

Replies to this message:
 Message 73 by NoNukes, posted 12-21-2013 8:39 AM PlanManStan has replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 74 of 76 (714301)
12-21-2013 10:10 AM
Reply to: Message 73 by NoNukes
12-21-2013 8:39 AM


Re: Stop asserting and provide an argument.
"You claim the dictionary is wrong without citing any source. You claim that terminology is wrong without citing any examples of the terminology being used in the way you suggest. And then you don't see to recall the silly stuff you've posted and insist that I point quote back your folly to you."
Firstly, I never said that the dictionary was wrong, I said that the dictionary form is somewhat, well, useless because people commonly use words almost oppositely than what they actually are supposed to mean (and yes, I did provide an example). Secondly, a perfect example of how 'damage' could be incorrect when talking about genetic mutations is that the word 'damage' as it is commonly used implies tampering, often times active and intentional tampering. Thirdly, I posted those quotes to remind you of things I have said, such as when you said that I was a re-hashing of someone else.
I've never insisted that you quote me back! If I have, it was an accident, but I'd like it if you'd provide me with a quote of me doing so. (That was a postitve statement, so I'd like some backup)

This message is a reply to:
 Message 73 by NoNukes, posted 12-21-2013 8:39 AM NoNukes has replied

Replies to this message:
 Message 75 by NoNukes, posted 12-21-2013 11:07 AM PlanManStan has replied

  
PlanManStan
Member (Idle past 3718 days)
Posts: 73
Joined: 12-12-2013


Message 76 of 76 (714313)
12-21-2013 11:44 AM
Reply to: Message 75 by NoNukes
12-21-2013 11:07 AM


Re: Stop asserting and provide an argument.
Meh. Maybe you're right. But I'd like to get back to the what this thread was originally intended for.

This message is a reply to:
 Message 75 by NoNukes, posted 12-21-2013 11:07 AM NoNukes has seen this message but not replied

  
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