As we gain the ability to manipulate genes, will we be able to effectively hyper accelerate the evolutionary process?
You should just leave out altogether the idea of a hyper-evolutionary process. What you are talking about is genetic engineering or manipulation. This is outside the scope of the evolutionary meaning, populations evolving over thousands of generations.
Are we becoming the stewards of our own genome?
Yes, I would say so.
Are we up to it?
As in mankind is benefited over the long term? I would say anyone's guess. As a general rule decreased variation is more susceptible to extinction.