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Author Topic:   How to make a ribozyme (using abiotic starting compounds)
molbiogirl
Member (Idle past 2672 days)
Posts: 1909
From: MO
Joined: 06-06-2007


Message 43 of 55 (412078)
07-23-2007 5:50 PM
Reply to: Message 42 by Rob
07-23-2007 9:22 AM


Re: Polymerisation: Synthesis of Ribose Nucleic Acid Strands
The soure of energy for these reactions is stuff like ATP and GTP.
Nope.
Today's organisms use three types of energy sources: fermentation, photosynthesis and respiration. None of these energy sources has been linked directly to the origin of life. A fourth energy source, ”thermosynthesis,’ free energy gain from thermal cycling, was proposed in a theoretical model for the emergence of the chemiosmotic machinery ...
http://www.arxiv.org/pdf/q-bio.PE/0501013
Of course modern ATP synthase didn't exist back then. Nobody's claiming it did. Except you, I mean.
Furthermore. The polymerization was probably catalyzed. Catalyzation of this sort has been done in the lab. The catalyzed polymerization rate was greater than the uncatalyzed polymerization rate by a factor of 10e9. (Gosh darn it! What's the code for "superscript"? I hate this whole 10e9 business.) Anyway. That's a billion to you and me.
The catalyzed polymerization rate is really thermodynamically favored. That means that the reaction is going to be "pushed" in the direction of polymerization. ATP is not necessary. Actually, nothing else is necessary. It's like putting a ball on the side of a mountain. It's gonna roll down hill. The energy state of the ball at the bottom of the hill is lower than the energy state of the ball on the side of the mountain. So it will happen.

This message is a reply to:
 Message 42 by Rob, posted 07-23-2007 9:22 AM Rob has replied

Replies to this message:
 Message 44 by ringo, posted 07-23-2007 6:03 PM molbiogirl has replied
 Message 47 by Rob, posted 07-23-2007 10:50 PM molbiogirl has not replied
 Message 50 by Rob, posted 07-26-2007 10:36 AM molbiogirl has not replied

  
molbiogirl
Member (Idle past 2672 days)
Posts: 1909
From: MO
Joined: 06-06-2007


Message 45 of 55 (412090)
07-23-2007 6:16 PM
Reply to: Message 44 by ringo
07-23-2007 6:03 PM


Re: Polymerisation: Synthesis of Ribose Nucleic Acid Strands
Mercy bow coo, Ringo!

This message is a reply to:
 Message 44 by ringo, posted 07-23-2007 6:03 PM ringo has not replied

Replies to this message:
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