quote:
Originally posted by KingPenguin:
by dormant i meant ignored by the mRNA.
KingPenguin: I don’t know if this answers your question, but I think I know what you're referring to.
mRNA is the translator for genetic information. All it does is copy (transcribe) relevant portions of a DNA strand. Then it cuts out the introns and splices the exons into a single chain that allows tRNA to copy the relevant triplets. It’s the tRNA that actually codes (translates) the amino acids that form the protein. Here’s what I mean:
This is followed by the tRNA translation into proteins:
The three translation steps shown are Initiation, Elongation, and Termination. The Met-Ala-Trp chain you see forming is the new protein. Any good biology book can give you a much more detailed description.
mRNA cannot be dormant. It can, however, be damaged by mutation (splice-site mutation). If a mutation alters one of the nucleotide signals that tell pre-mRNA what to cut out, then the intron is not removed and remains as part of the final mRNA molecule. The translation of the mRNA sequence alters the sequence of the final protein product.
Hope this helps.
[This message has been edited by Quetzal, 02-14-2002]