Shadow71 writes:
I cannot accept that these functions are randomly performed
JonF writes:
Reality is not affected by what you can or cannot accept.
Please read my message 643 where I present proof of dedicated, nonrandom, beneficial change and tell me if that is reality.
Your "I cannot accept that these functions are randomly performed" still does not affect reality.
The information in the paper you linked to appears to me to be reality. It is not anything that challenges the modern synthesis, or that is evidence of directed mutation or directed evolution.