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Author Topic:   Self-Replicating Molecules - Life's Building Blocks (Part II)
Member (Idle past 1766 days)
Posts: 128
Joined: 10-26-2010

Message 20 of 97 (612871)
04-19-2011 4:55 PM
Reply to: Message 8 by Dr Jack
07-04-2009 1:24 PM

Mr Jack writes:
Two tailed lipids will spontaneously form bilayered spheres (called liposomes), yes, but one-tailed lipids (aka detergents) form micelles (little balls without an inside) instead - and here's the problem - detergents disrupt the formation of liposomes.
I'm not sure how this problem is supposed to be addressed.
lipids can also stack into 1 dimensional structures.
In the primordial ocean, these would grow from the ends until they became capped but some (possible rare) side linking subunits could link to the sides and thereby allow the structure to branch. These molecules would reproduce but could not evolve.
to get a fully RNA-like self reproducing molecule (capable of evolving) you would need some kind of environmental selection that would concentrate these side linking subunits until they were nearly all that was left.
PAH world hypothesis - Wikipedia
Polycyclic aromatic hydrocarbons are the most common and abundant of the known polyatomic molecules in the visible Universe, and are considered a likely constituent of the primordial sea.[4] PAHs, along with fullerenes (or "buckyballs"), have been recently detected in nebulae.
PAH's are not normally very soluble in sea water, but when subject to ionizing radiation such as solar UV light, the outer hydrogen atoms can be stripped off and replaced with a hydroxyl group, rendering the PAHs far more soluble in water.
These modified PAHs are amphiphilic, which means that they have parts that are both hydrophilic and hydrophobic. When in solution, they assemble in discotic mesogenic stacks which, like lipids, tend to organize with their hydrophobic parts protected.
Edited by granpa, : spelling
Edited by granpa, : clarification
Edited by granpa, : add color and remove side material
Edited by granpa, : clarification
Edited by granpa, : added quote of message I am replying to.
Edited by granpa, : become capped
Edited by granpa, : In the primordial ocean

This message is a reply to:
 Message 8 by Dr Jack, posted 07-04-2009 1:24 PM Dr Jack has not replied

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