Exposing the evolution theory. Part 2

Kleinman:

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You, Tangle, and biologists are wrong about the physics and mathematics of biological evolution.

AZPaul3:

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So says the religious charlatan desperately trying to make his god relevant again.

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You still can't explain the mathematical reason it takes a billion replications for each adaptive step in the Kishony and Lenski biological evolutionary experiments. And neither can biologists. AZPaul3, you are a sucker that has swallowed a bad story hook, line, and sinker.

Observe my avatar ... as you can see, it is not spewing idiocy, but truth and wisdom.

Doesn’t matter. No one cares for your view. We don’t believe a thing you say. Go do all the phony math you want Kleinman.

As we all can clearly see, it's a scum-sucking bottom feeder.Besides, you are clearly the one committing the idiocy I describe in Message 879, so you are clearly identified.You willfully stupid idiot.

Kleinman:

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You still can't explain the mathematical ...

AZPaul3:

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Doesn’t matter. No one cares for your view. We don’t believe a thing you say. Go do all the phony math you want Kleinman.

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It's not just the mathematics, it is the experimental evidence that reveals this as well. You may not care or be able to do the mathematics of biological evolution, but people suffering from drug-resistant infections and failed cancer treatments might care. Biologists have failed society and AZPaul3 has swallowed their story hook, line, and sinker. You ignore the results of the Kishony and Lenski biological evolutionary experiments because they don't agree with your belief system.

Your bizarre rant in Message 897 was an exercise in irrelevance. Sorry.

Kleinman, we see your religious zealotry and thus your motivation to lie. No one is believing your crap. Doesn't matter what you think of me or biologists or society.We know how mutation actually happens, how drug resistance actually happens, how life and evolution and genetics actually happen.Your fairy tales, your wailing and gnashing of teeth against evolution and against science, mean nothing. The reality is already known.

Go ahead and name the 100 million. I'm waiting.

You won't understand this but the biologists looking on will.Name 100 million nested hierarchies, all of them biological:AnimaliaMore than 100 million species populations each within multiple nested hierarchies.So, sensei, where is this data that falls outside of common ancestor predictions?
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You said you had some. Can we see it or are you still lying? Still lying aren't you.

The troll returns

Even nonbiologists should understand. The fundies will refuse to understand.

Kleinman:

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Biologists have failed society and AZPaul3 has swallowed their story hook, line, and sinker.

AZPaul3:

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Kleinman, we see your religious zealotry and thus your motivation to lie. No one is believing your crap. Doesn't matter what you think of me or biologists or society.
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We know how mutation actually happens, how drug resistance actually happens, how life and evolution and genetics actually happen.
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Your fairy tales, your wailing and gnashing of teeth against evolution and against science, mean nothing. The reality is already known.

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AZPaul3, I am not lying. Descent with modification and adaptation obeys specific mathematical principles and scientific laws. Mutations are random events, so the joint probability (the probability that two or more particular mutations will occur on a member in a lineage) determines the probability that it will occur. Drug resistance requires that a lineage of bacteria accumulate a particular set of mutations. Biologists have not done this math. In my medical practice, I see drug-resistant infections, but nothing I had learned in my many years of study of biology explains how this happens. The mathematics for this process was presented to experts in the field of probability theory and the application of this mathematics to medical problems at Statistics in Medicine". They peer-reviewed the math and the experimental examples from the medical field and found that the math was correct. It wasn't hard for them to peer review this paper. The math is actually very simple and is taught in introductory probability theory courses taught at the high school level. Anyone familiar with the mathematics of coin tossing or dice rolling can understand and do this math. You can deny this all you want but the math is very simple that explains how a lineage accumulates a set of adaptive mutations. You could easily learn this math if you watched the YouTube videos on the subject from Khan Academy or Professor Leonard geared toward high school students. You may find these papers contradict your understanding of biological evolution but the math fits the experimental data. Some day, if you start to care about drug-resistant infections or why cancer treatments fail, read these papers, and understand how biological evolution actually works.
For a single selection pressure:
The basic science and mathematics of random mutation and natural selection
And for multiple simultaneous selection pressures:
The mathematics of random mutation and natural selection for multiple simultaneous selection pressures and the evolution of antimicrobial drug resistance
If you actually ever read these papers and understand what they say and still think they are wrong, I've given you a website, Retraction Watch – Tracking retractions as a window into the scientific process , report it to them and I'm sure that the publisher "John C. Wiley" will have them removed. But they won't because the peer reviewers went through these papers with a fine-toothed comb and found them correct.

sensi:

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Go ahead and name the 100 million. I'm waiting.

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Hi sensi, the reason why these nested hierarchies are baloney is that these are just another name for "family tree" and biologists don't understand how descent with modification and adaptation works. From the following website:
Nested hierarchies - Understanding Evolution The problem for biologists is that they have failed to correctly do the mathematics of descent with modification and adaptation. They can't even show how humans and chimpanzees came from a common ancestor. Taq tried to show that ERVs which later turned out to be LTRs show that they are related and his best argument is to call me a "f---ing moron". Perhaps he is trying to show that his skills as a debater are on par with his skills as a biologist. Taq and other biologists don't understand that it takes huge populations for descent with modification and adaptation to operate. The Kishony and Lenski biological evolutionary experiments demonstrate it. It takes a billion replications for each adaptive mutation to occur on the correct lineage. If you have a replicator in a multiple selection pressure environment, descent with modification and adaptation needs exponentially larger populations to adapt. This is why 3-drug therapy is used to treat HIV. Even HIV can't reach the population size required for descent with modification and adaptation to operate. If you want to understand the math, you can read these two papers that show how to compute those probabilities:
For a single selection pressure:
The basic science and mathematics of random mutation and natural selection
And for multiple simultaneous selection pressures:
The mathematics of random mutation and natural selection for multiple simultaneous selection pressures and the evolution of antimicrobial drug resistance
You can also formulate these problems as a Markov Process as we have discussed previously. It gives equivalent results but the computational effort is much greater.If you include biological competition, this slows the descent with modification and adaptation process even further. This is why the Lenski experiment evolves much more slowly thant the Kishony experiment. Here's a paper that shows how to do the mathematics for the Lenski experiment:
Fixation and Adaptation in the Lenski E. coli Long Term Evolution Experiment
And here's a short presentation video that helps show how you do the arithmetic:
The Lenski Long Term Evolution ExperimentBiologists have failed to understand these simple mathematical principles and correctly explain how biological evolution works. That's why they haven't described how drug resistance evolves or why cancer treatments fail, or given a correct explanation of the Kishony and Lenski biological evolutionary experiments.

Theodoric:

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The troll returns

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You don't have much to contribute to this discussion.

Theodoric:

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Even nonbiologists should understand. The fundies will refuse to understand.

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Maybe you want to try and post a link to a paper that explains how drug resistance evolves and why cancer treatments fail. Biologists have failed to give this explanation. And don't forget to post a quote from the paper that gives that explanation.