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Author Topic:   Evidence against chromosome 2 fusion???
Genomicus
Member (Idle past 1941 days)
Posts: 852
Joined: 02-15-2012


(1)
Message 4 of 10 (688408)
01-22-2013 11:22 AM
Reply to: Message 1 by herebedragons
01-21-2013 7:39 PM


I hope to cover this in more depth later on, but for right now I'll limit myself to a few points.
The link to the video is not listed in the OP, but I suspect the video is the following:
I haven't read the ICR articles, but I watched the video and have the following points in mind:
1. In reference 1 in the description box, the genomic region that was searched was 114,251,945-114,426,678. But the Nature paper never mentioned this region, so I have no idea where this number came from. I posted a comment on the video with that inquiry, and hopefully it'll go through the comment pending.
2. The Nature paper linked to above states that the fusion site is located in 2q13—2q14.1 of chromosome 2. I searched for subtelomeric sequences in various areas of this region, using the NCBI Human Map Viewer, with the result that there are quite a few TTAGGG repeats, but few of them are directly in sequence (i.e., very few TTAGGGTTAGGG repeats).
3. The maker of the video states that:
"The article mentions the region name, which contains more than 160,000 BP. I copied the entire sequence into a text editor, then searched for part of the sequence that was displayed in the article, for which I found one match as predicted. I then recorded the location that the 798 BP sequence started relative to my starting point, and then recorded the location of the predicted fusion relative to the start of the 798 BP sequence."
Not sure what article he's referring to, but if it's the Nature paper then it never mentions a region of ~160,000 bp.
This is just a cursory overview. I'll see what the ICR articles have to say, and then provide my thoughts on that.
Edited by Genomicus, : No reason given.
Edited by Genomicus, : No reason given.

This message is a reply to:
 Message 1 by herebedragons, posted 01-21-2013 7:39 PM herebedragons has replied

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Genomicus
Member (Idle past 1941 days)
Posts: 852
Joined: 02-15-2012


Message 7 of 10 (688627)
01-24-2013 12:13 AM
Reply to: Message 6 by herebedragons
01-23-2013 9:55 AM


Re: More than one step
Another link you might find of interest: here.

This message is a reply to:
 Message 6 by herebedragons, posted 01-23-2013 9:55 AM herebedragons has not replied

  
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