I think the question is what selection pressures are there on humans?
There is always the selective pressure involved with attracting a mate. This won't go away no matter how insulated humans become from environmental forces, and no longer having to compete physically with predators and prey animals.
Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
The apathy of the people is enough to make every statue leap from its pedestal and hasten the resurrection of the dead. William Lloyd Garrison.
It's not too late to register to vote. State Registration Deadlines