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Author Topic:   Comparisons of Neandertal mtDNA with modern humans and modern chimpanzees
coffee_addict
Member (Idle past 502 days)
Posts: 3645
From: Indianapolis, IN
Joined: 03-29-2004


Message 16 of 80 (104850)
05-03-2004 1:29 AM
Reply to: Message 12 by redwolf
05-02-2004 11:38 PM


redwolf writes:
Basically, somebody who wanted to go on believing that modern man had evolved would have to come up with some new hominid, closer to us (than the neanderthal) in both time and morphology, to claim as a human ancestor.
I don't mean to whip out logic on you, but what you've done is commit a fallacy called appeal to ignorance.
You are basically saying that just because we haven't found a homonid close enough to modern man that such a homonid doesn't exist. Drawing a conclusion from an incomplete record is as ignorant as anyone can get.
Edited-wrong info.
[This message has been edited Lam, 05-03-2004]

The Laminator

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Sylas
Member (Idle past 5285 days)
Posts: 766
From: Newcastle, Australia
Joined: 11-17-2002


Message 17 of 80 (104856)
05-03-2004 2:01 AM
Reply to: Message 16 by coffee_addict
05-03-2004 1:29 AM


Lam writes:
You are basically saying that just because we haven't found a homonid close enough to modern man that such a homonid doesn't exist. Drawing a conclusion from an incomplete record is as ignorant as anyone can get.
More to the point, we do have the remains of such hominids; many of them. Redwolf even mentions some, but his discussion is flawed by various other errors. I'm sure we'll discuss this some more as the thread continues.
Neanderthal works and remains have only been found in Europe, not all over the map. Get your facts straight!
Neadertal remains have been found more a bit more widely than this. As well as finds in Europe, there are finds in Syria, Israel, Uzbekistan, Morocco and Iraq. Some of these fossils are described at Homo neanderthalensis, at Stephen Heslip's pages at Michigan State University, for a course on Hominid Fossils.
Cheers -- Sylas

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coffee_addict
Member (Idle past 502 days)
Posts: 3645
From: Indianapolis, IN
Joined: 03-29-2004


Message 18 of 80 (104858)
05-03-2004 2:10 AM
Reply to: Message 17 by Sylas
05-03-2004 2:01 AM


Sylas writes:
Neadertal remains have been found more a bit more widely than this. As well as finds in Europe, there are finds in Syria, Israel, Uzbekistan, Morocco and Iraq. Some of these fossils are described at Homo neanderthalensis, at Stephen Heslip's pages at Michigan State University, for a course on Hominid Fossils.
Really now. My bad.
I've always thought they were unique to Europe. Oh well.
What about Africa? Has there been findings of them in Africa?

The Laminator

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Sylas
Member (Idle past 5285 days)
Posts: 766
From: Newcastle, Australia
Joined: 11-17-2002


Message 19 of 80 (104863)
05-03-2004 2:25 AM
Reply to: Message 18 by coffee_addict
05-03-2004 2:10 AM


Lam writes:
What about Africa? Has there been findings of them in Africa?
Not that I know of. The find at Jebel Irhoud, which is the basis for my listing Morroco in the previous post, would be Africa. It is just across from Gibraltar, but I think the identification with Neandertal may be contentious.
The Neandertal range is given by Francis Steen as follows:
Map of Neandertal range {Image is a link to source; uses current browser window}

The source for this map is the same that redwolf used in Message 9 for skull pictures. Seems to be comprehensive and high quality, with copious references to diverse views within the scientific community. Thanks for the reference.
Cheers -- Sylas
Edit change. The map was previously taken from Neanderthal Sites (by D.S. McDonald). It is now taken from a different source, used by redwolf, and is properly linked.
[This message has been edited Sylas, 05-03-2004]

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JonF
Member (Idle past 193 days)
Posts: 6174
Joined: 06-23-2003


Message 20 of 80 (104912)
05-03-2004 9:44 AM
Reply to: Message 9 by redwolf
05-02-2004 11:09 PM


For anybody who hasn't really followed the argument, the question as to whether the neanderthal dna findings would justify a claim that the neanderthal was "about halfway between us and chimpanzees" is not crucial to the case I would try to make. That's just a figure of speech.
ROFLMAO!
To anybody who has followed the argument, the claim and case you made was that neandertals were literally about halfway between humans and chimpanzees and neandertals were not our ancestors (see http://EvC Forum: Aquatic Ape theory? -->EvC Forum: Aquatic Ape theory?); nothing more and nothing less. It wasn't a figure of speech, you argued for its literal truth, and you were flat-out wrong.

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redwolf
Member (Idle past 5816 days)
Posts: 185
From: alexandria va usa
Joined: 04-13-2004


Message 21 of 80 (104913)
05-03-2004 9:48 AM
Reply to: Message 17 by Sylas
05-03-2004 2:01 AM



More to the point, we do have the remains of such hominids; many of them. Redwolf even mentions some, but his discussion is flawed by various other errors. I'm sure we'll discuss this some more as the thread continues.
Nonetheless, it seems clear enough that that does not save the picture for purposes of evolution.
When they used to draw homonid progressions leading up to modern man (which you say you don't like), the final two things before modern man were homo erectus, and neanderthal, it seeming obvious to scientists that the neanderthal was the closest (morphologically) hominid to us, and then erectus, and then the guys further down and back.
Depending on whose picture of archaic homo sapiens you use, you are either still trying to claim that modern man descended from something essentially identical to the neanderthal, which has been coercively disproven by the combination of the dna studies and Shreeve's study, or you are trying to claim that something marginally different from us descended from homo erectus, which is a great deal more apelike than the neanderthal, which nobody should believe in light of the recent findings.
Moreover, there aren't "many" of these. The one skull in terribly bad shape is said to be the most complete, and they appear to be rare. Too rare for modern man to be descended from them.

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Sylas
Member (Idle past 5285 days)
Posts: 766
From: Newcastle, Australia
Joined: 11-17-2002


Message 22 of 80 (104926)
05-03-2004 11:31 AM
Reply to: Message 14 by redwolf
05-03-2004 1:16 AM


Shreeve and I both disagree with redwolf
redwolf writes:
Sylas writes:
The first phrase is true, and the second is false. The findings do not give any indication that interbreeding was precluded. They only indicate that there was no detectable genetic contribution made. These are different claims.
The paper indicates that the difference between Humans and Neandertals is less than the difference between Western and Eastern varieties of the common chimpanzees... and they are completely interfertile, and yet also with distinct gene pools because interbreeding does not usually occur.
I posted this the other day and you supposedly read it. Here it is again:
http://www.findarticles.com/..._86/70362289/p2/article.jhtml

"...Following the discovery of the Neanderthal DNA, the German scientists compared it to the DNA of humans living today. (No early modern human DNA has ever been uncovered.) A clear difference was apparent between the two types of DNA. So marked was that difference that the Germans concluded that Neanderthals were an entirely separate species of human. A species is a group of organisms that have common characteristics and cannot breed with another species.
Because of the distinct difference in DNA, any attempts at interbreeding by Neanderthals and the early modern humans would have failed to yield offspring, the scientists reasoned."
Again, James Shreeve made an overwhelming case for the impossibility of crossbreeding between neanderthals and modern man and this paper is generally acepted as definitive on the subject at this point. The dna findings basically just confirmed Shreeve's analysis.
I read it better than you, apparently! The very next paragraph after the bit redwolf gives in red reads as follows (my emphasis in bold).
How, then, could the Lagar Velho child be of mixed Neanderthal--early modern human background? Even newer biological evidence suggests that the Germans may have been wrong in their conclusion about DNA differences, Zilhao writes in a recent issue of Archaeology magazine. Shortly after the publication of the German scientists' DNA analysis, the results of a separate study of chimpanzee DNA were released.
Did you read that bit?
Yes, I read your link, and the other ones you gave also. You can get all kinds of diverse opinions on this. I have no problem if it turns out that Shreeve disagrees with me, and indeed no problem if there is new evidence that leads me to change my mind. Interbreeding, and interfertility, are still open questions, and the data continues to be collected and examined and tested in various new ways. Shreeve is explicit about this in the end of the article you have quoted:
In any case, archaeologists keep digging. Future discoveries may yet reveal whether the early modern humans saw the Neanderthals as people like themselves and mingled with them to produce hybrids like the Lagar Velho child, or whether they kept their genetic distance.
Here are a couple more points you should note.
  • Shreeve is a well regarded science writer, but not actually a scientist. He has written some interesting books on Neanderthals, which have been widely praised; but they are not definitive works by any means. They review work by others, and present his own speculations on the matter.
  • Shreeve's own speculations on the lack of interbreeding are that the two species may well have been interfertile, but that interbreeding did not occur because of different mate recognition signals. The argument for this is entirely circumstantial, but worthy of serious consideration. Shreeve himself recognizes this as speculation.
  • The bit you placed in red is not Shreeve's own view, but the way Shreeve describes the views of unnamed German scientists. Shreeve gives no citation and does not name the scientists, but most likely he is referring to Krings et al, whom we have discussed here at some length. The clue is that in the previous page of your link, Shreeve refers to DNA extracted from an arm bone; this is just what Krings et al did. In this case, Shreeve is wrong. The bit that he gives in red does not actually correspond to the views expressed by Krings et al. If you disagree, give a quote from the primary sources. The links are available in Message 1. But don't bother. The truth is that the scientists involved limited their conclusions to the notion that there was no genetic contribution to the gene pool; not that the differences were too great for breeding to be possible. In fact, they gave the comparison with chimpanzee subspecies, suggestive that they were interfertile, even though little to no breeding took place.
  • In your second link, Shreeve does not make a definitive case, but a speculation, by his own description. Quoting from your second link... (my emphasis):
    Although it is merely a speculation, the idea fits some of the facts and solves some of the problems. Certainly the Neanderthals' ancestors were geographically cut off from other populations enough to allow some new mate-recognition system to emerge. During glacial periods, contact through Asia was blocked by the polar glaciers and vast uninhabitable tundra. Mountain glaciers between the Black and Caspian Seas all but completed a barrier to the south. "The Neanderthals are a textbook case for how to get a separate species," archeologist John Shea told me. "Isolate them for 100,000 years, then melt the glaciers and let 'em loose."
    If mate recognition lay behind a species-level difference between Neanderthals and moderns, the Levantine paradox can finally be put to rest. Their cohabitation with moderns no longer needs explanation. Neanderthals and moderns managed to coexist through long millennia, doing the same humanlike things but without interbreeding, simply because the issue never really came up.
    That is, Shreeve disagrees with your extreme position. He considers that the reason for lack of interbreeding was not lack of fertility, but lack of desire.
    In fact, your second link is a rather beautiful and thought provoking speculation. I enjoyed it, and it is intriguing to wonder what human history would have been like if our Neandertal cousins had survived.
In the meantime, my extract quoted above remains unambiguously true; it is a straight description of the actual data which we need to consider. The actual empirical data indicates that the genetic difference between Neandertals and Humans was less than the difference between interfertile subspecies of the common chimpanzee, and much less than the difference between common chimpanzee and bonobos, which are also interfertile.
Indeed Shreeve mentions this himself, in your first linked article!
Shreeve's speculation (not analysis) is an attempt to reconcile the evidence I have cited on comparisons with chimpanzee diversity (which indicated that Neadertals probably were interfertile with Homo sapiens) and the genetic evidence of Krings et al (which suggests that Neadertals did not contribute to the modern gene pool). And even then, Shreeve acknowledges that there is room for future evidence to contribute further understanding. I agree with him on all these three points; and I think his proposed solution, of lack of mate recognition, is very plausible.
I think you need to read that article again, and more carefully.
Cheers -- Sylas
PS. You would be better to remove "?term=" from your link to the first Shreeve article. I have removed it from the URL in the quoted extract from your post. Link construction code here fails to parse the "=" as part of the link. You can also work around the problem by making the links explicitly, rather than leaving a bare URL in your post.

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Replies to this message:
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jar
Member (Idle past 419 days)
Posts: 34026
From: Texas!!
Joined: 04-20-2004


Message 23 of 80 (104931)
05-03-2004 12:14 PM
Reply to: Message 18 by coffee_addict
05-03-2004 2:10 AM


TTBOMK, none from Africa...
however there have been finds all across the northern and eastern shores of the Med. That would lead me to belive that it is certainly possible if not even likely that we will oneday find examples of Neanderthal habitation along the southern shore of the Med as well.

Aslan is not a Tame Lion

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RAZD
Member (Idle past 1430 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


Message 24 of 80 (104955)
05-03-2004 1:57 PM
Reply to: Message 22 by Sylas
05-03-2004 11:31 AM


Re: Shreeve and I both disagree with redwolf
Another possibility is that the interbred offspring were infertile - mules. This would allow a child or any individual specimen to have mixed DNA, but still no neander DNA in human genome.
Personally I have wondered if the temporal overlap between sapiens and neander is the root of the troll and ogre myths. This would shed some light on group interactions. I suppose one could do a search on the location origins of the myths and see if they match the population data to get some inference of validity, but it would be extremely difficult to make more than a hypothetical case.

we are limited in our ability to understand
by our ability to understand
RebelAAmerican.Zen[Deist
{{{Buddha walks off laughing with joy}}}

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redwolf
Member (Idle past 5816 days)
Posts: 185
From: alexandria va usa
Joined: 04-13-2004


Message 25 of 80 (104965)
05-03-2004 3:00 PM
Reply to: Message 22 by Sylas
05-03-2004 11:31 AM


Re: Shreeve and I both disagree with redwolf
>Did you read that bit?
No. I stopped reading at the point of the German scientists claiming that interbreeding would not be possible. I was trying to look at several such articles and was in too much of a hurry.
Nonetheless, the one or two skeletons which anybody is making any such claims for could be anything and do not come close to answering the mail for the problem which Shreeve notes, i.e. that you had the two groups living close to eachother for very long periods of time, and that if interbreeding was possible, there should be crossbreed skeletons all over the place; they should be very easy to find.
It's also interesting that the one skeleton anybody is claiming as a crossbreed skeleton is that of a child; that may be as long as such crossbreeds ever lived.

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redwolf
Member (Idle past 5816 days)
Posts: 185
From: alexandria va usa
Joined: 04-13-2004


Message 26 of 80 (104966)
05-03-2004 3:06 PM
Reply to: Message 2 by AdminAsgara
05-01-2004 10:13 PM


Are members allowed to post on the 'proposed new topic' area?

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AdminSylas
Inactive Member


Message 27 of 80 (105017)
05-03-2004 5:22 PM
Reply to: Message 26 by redwolf
05-03-2004 3:06 PM


Off topic. posting new proposals
Members can post new topics in Proposed New Topics, but they can't add posts to a thread. Moderators will approve new topics into the appropriate forum, after which all members may join in.
For more details, see Message 1 and following, and Message 53. And discussion or comments is being actively solicited, and is very welcome. Please give it in those threads, not in followup to this thread.
AdminSylas

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RAZD
Member (Idle past 1430 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


Message 28 of 80 (105021)
05-03-2004 5:25 PM
Reply to: Message 15 by RAZD
05-03-2004 1:22 AM


(ps for ted re posting new topics)
I have extended the photo gallery from my previous message:
A Cro magnon skull specimen has been added at the front, while Homo habilis and Homo rudolfensis have been added at the end.
I have also shown the "calibration" lines that I used to size the pictures in order to take out variation that could be from individual specimens and to show relative proportions.
This is in answer to the claim by redwolf\ted that there is a major discontinuity in the family tree (Note that his "archaic" Homo sapiens is now considered Homo heidelbergensis and is shown as such here).
Enjoy.
ps - ted: the New Proposed Topics is the place to start new topics, see http://EvC Forum: HOW TO START A NEW TOPIC (as of 4/13/04)
[This message has been edited RAZD, 05-03-2004]

we are limited in our ability to understand
by our ability to understand
RebelAAmerican.Zen[Deist
{{{Buddha walks off laughing with joy}}}

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sfs
Member (Idle past 2559 days)
Posts: 464
From: Cambridge, MA USA
Joined: 08-27-2003


Message 29 of 80 (105029)
05-03-2004 5:51 PM
Reply to: Message 8 by Sylas
05-02-2004 11:03 PM


Re: comparison with chimpazee diversity
No; that was the HVRII. There was no difference given for the HVRI, which was the subject of my second plot.
Sorry, I wasn't paying attention. (Maybe I shouldn't have had a Buffy episode on in another window.)
I'm collecting a set of references for this. Can you give a cite where I could track down more on these, please? Does mtDNA diversity give any different result to nuclear DNA diversity?
Yu N, Jensen-Seaman MI, Chemnick L, Kidd JR, Deinard AS, Ryder O, Kidd KK, Li WH. Low nucleotide diversity in chimpanzees and bonobos.
Genetics. 2003 Aug;164(4):1511-8.
There's also data from the chimp genome effort on western and central chimps -- it's the actual source I was using, but it hasn't been published yet. It will be available Real Soon Now.

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Sylas
Member (Idle past 5285 days)
Posts: 766
From: Newcastle, Australia
Joined: 11-17-2002


Message 30 of 80 (105034)
05-03-2004 6:08 PM
Reply to: Message 29 by sfs
05-03-2004 5:51 PM


Chimpanzee subspecies cross-breeding?
sfs writes:
Sorry, I wasn't paying attention. (Maybe I shouldn't have had a Buffy episode on in another window.)
Sheesh -- get your priorities right. You should always have a Buffy episode on in another window.
I have another question, which you or others may be able to help me with. In previous posts, I have assumed that the chimpanzee subspecies are interfertile. However, I can't confirm this; and on checking I could be wrong.
It seems that the close similarity indicates to most researchers that hybrids are extremely likely, and if I recall correctly, conservation groups advocate that chimpanzees in captivity should be maintained in their distinct subspecies in order to prevent cross breeding and loss of diversity.
Is anyone aware of whether or not there are any confirmed instances of fertile hybrid offspring from any of the chimpanzee subspecies? Are there any populations of distinct subspecies which are in contact with each other, so that interactions across subspecies lines would be possible?
Cheers -- Sylas

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