The spread of good mutations in sexually reproducing organizms

In sexually reproducing organisms how do good mutations overcome both genetic drift and genetic burden?Genetic drift maintains the status quo quite well, but if you minimize genetic drift by having an inbred population harmful mutations will quickly build up and weaken the entire population since the majority of mutations will always decrease rather than increase general health.How do both genetic drift and genetic burden get overcome so that a good mutation can both spread through the population and not be coupled with many bad mutations?

This seems to be a worthwhile topic, it might be helpful if you explained a bit more about what genetic drift and genetic burden are. While those who are likely to be able to answer your question may be familiar with these terms others interested in the topic may not.TTFN,AW

lol, holy cow was my understanding off! I'm not even sure I have a question to post anymore.well, I have to go to work, I'll look at this again later....This message has been edited by mrjeremy, 12-22-2005 09:50 AM

Your description of genetic drift is severely at odds with the common usage of the term. This section from the text book 'Modern Genetic Analysis' describes the commonly understood meaning of genetic drift.When you are satisfied with your examples could you use the 'edit' option to redraft your opening post to incorporate them, as some people will reply to that rather than reading the subsequents post beforehand.TTFN,AW

Hello, Mr.Jeremy! Did you want to reword this topic and continue with it? If so, let me know by the end of January. You appear quite articulate (yet busy!) If you get some time and want to start a discussion, drop us a line! Reword the O.P. (or change it entirely) by pushing the EDIT button. You can even start with a new title, if you wish.

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