Exposing the evolution theory. Part 2

Theodorkic appears to be the resident troll-watchman ... without his diligent observations, trolls could slip in past the city gates unnoticed.

Dredge:

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Theodorkic appears to be the resident troll-watchman ... without his diligent observations, trolls could slip in past the city gates unnoticed.

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He's not the only one. There are a few that post that has nothing to offer. Now they can post and tell us how much they have to offer.

Of course you are lying. That was established in your first few posts here many moons ago. But you go on with your errant logic and faulty math for all the rest of the world to ignore.Note how your great life-saving and super important discoveries have gone unnoticed by humanity. Notice how the fault is alway with the thousands of scientist all being too stupid to comprehend your oh-so-easy to understand math. You are the great revealing genius who just can't convince the best minds in the world of your stature.This is one of the signature characteristics of the mental looney. That's you, Kleinman.Another telling feature of the mentally deficient superego nutjob (that's you, too, Kleinman) being the fixation on your errant self-published fantasy papers that, despite their obvious revolutionary life-saving discoveries, have been totally ignored by the scientific community.Despite their being shown bogus you are compelled to boast and display them as the hard evidence of your brilliance. You are a lying religious nutjob, Kleinman.

Kleinman:

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AZPaul3, I am not lying.

AZZPaul3:

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Of course you are lying.

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So, why don't you tell us how drug resistance evolves and why cancer treatments fail?

One-note Kleinman in keeping with his demented form.

Confirming his diagnosis of you for the 1890'th time. Refer Message 903.

Kleinman:

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So, why don't you tell us how drug resistance evolves and why cancer treatments fail?

AZPaul3:

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One-note Kleinman in keeping with his demented form.

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What's the matter, don't you and biologists know the tune? Why can't you and biologists explain to us how drug resistance evolves and why cancer treatments fail? It is a very simple question about evolutionary biology. Here, I'll play it for you.
For a single selection pressure:
The basic science and mathematics of random mutation and natural selection
And for multiple simultaneous selection pressures:
The mathematics of random mutation and natural selection for multiple simultaneous selection pressures and the evolution of antimicrobial drug resistance
See how simple that is? That is the cue for you to play your tune. Make sure you blow hard.

Kleinman:

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Why can't you and biologists explain to us how drug resistance evolves and why cancer treatments fail?

AZPaul3:

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AZPaul3, you post a "bored" picture in response to a simple question to describe a biological phenomenon that is occurring today in many places around the world. There are many good laboratory experiments that demonstrate this phenomenon. The reason why you and biologists can't correctly describe this phenomenon is that you and biologists don't understand the physics and mathematics of biological evolution. You may be bored, and Taq can claim that you don't need mathematics to describe biological evolution but that doesn't change the fact that you and biologists are wrong and have failed to correctly describe and understand biological evolution. Try something other than an emoticon to explain real, measurable, and repeatable experimental evidence and the physics and mathematics which describes how these biological evolutionary experiments work.

dwise1:

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Confirming his diagnosis of you for the 1890'th time. Refer Message 903.

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Let's consider the knowledge and wisdom that AZPaul3 has in making medical diagnoses (in particular psychiatric diagnoses) since he is too bored to explain anything about biological evolution. From Message 903:

Kleinman:

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AZPaul3, I am not lying.

AZPaul3:

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Of course you are lying. That was established in your first few posts here many moons ago. But you go on with your errant logic and faulty math for all the rest of the world to ignore.
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Note how your great life-saving and super important discoveries have gone unnoticed by humanity. Notice how the fault is alway with the thousands of scientist all being too stupid to comprehend your oh-so-easy to understand math. You are the great revealing genius who just can't convince the best minds in the world of your stature.
​
This is one of the signature characteristics of the mental looney. That's you, Kleinman.
​
Another telling feature of the mentally deficient superego nutjob (that's you, too, Kleinman) being the fixation on your errant self-published fantasy papers that, despite their obvious revolutionary life-saving discoveries, have been totally ignored by the scientific community.
​
Despite their being shown bogus you are compelled to boast and display them as the hard evidence of your brilliance. You are a lying religious nutjob, Kleinman.

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Let's start with his claim that I go on with errant logic and faulty math (even though my math has been peer-reviewed and published). The Kishony and Lenski biological evolutionary experiments both demonstrate that it takes a billion replications for each adaptive step. Since you have demonstrated some knowledge of probability theory and descent with modification and adaptation is a stochastic process, you should recognize what the random trial(s) is/are and the possible outcomes for the random trials. You have a mutation rate, the probability of success in a single random trial. When that probability of success is very small as mutation rates tend to be, it will take many replications for the adaptive mutation to occur. Simply do the math and you can get a good estimate for the number of replications needed for the adaptive mutation to occur. If you have trouble doing the math for this case, try studying these two papers.
For a single selection condition:
The basic science and mathematics of random mutation and natural selection
And for multiple simultaneous selection pressures:
The mathematics of random mutation and natural selection for multiple simultaneous selection pressures and the evolution of antimicrobial drug resistance
See if you can find any errors in this math, you won't.So, what other evidence does AZPaul3 have that I'm a "mental looney"? Since I have had to make some psychiatric diagnoses on patients in the past, I'll give you some conditions necessary to do so. The kinds of things a physician does to make such a diagnosis includes the following, medical history, physical examination, and laboratory tests. Laboratory tests include blood tests, radiographic imaging, electrograms, and other studies as necessary.AZPaul3 has not done a physical examination or any laboratory tests on me and if he did, he would be charged with practicing medicine without a license. So we are left with AZPaul3's idea of medical history for my lunacy. When making a psychiatric diagnosis on someone with a loss of contact with reality, one should consider what the person's mental state has been in the past. Has this person shown behavior consistent with a loss of contact with reality? I have, in the past, gone to school and studied engineering and obtained a PhD degree in that subject. I worked a few years in the aerospace industry and part-time in the university system teaching engineering and at that time, I took the state professional engineering exam and passed it to become a licensed engineer. But I was still young and impulsive at that time, and my real interest was in medicine/engineering, so I decided to go to medical school. Some people may claim this was the act of a lunatic and they might be right. Anyway, I completed medical school, passed all my licensing examinations, and am now a licensed physician as well as a licensed engineer. I then worked for more than 30 years as a primary care physician. I did about 150,000 patient encounters, and no medical malpractice judgments or medical board complaints against me. And I decided to try and understand the evolution of drug resistance and why cancer treatment fails. I then published a few papers on what my studies showed. That's pretty crazy, isn't it dwise1.So, what is a possible conclusion that we can draw from AZPaul3's diagnosis? AZPaul3 believes that reptiles evolve into birds and fish evolve into mammals, and I'm crazy because I give an explanation of how drug resistance evolves and why cancer treatments fail based on the laws of physics, mathematics, and experimental results. I also explain why it takes a billion replications for each adaptive step in the Kishony and Lenski experiments using mathematics that you should understand. You should look for a second opinion when it comes to any medical diagnosis that AZPaul3 gives. You certainly shouldn't look to AZPaul3 for advice on how to do a probability calculation.

Wow. You almost got something right.Birds did descend from dinos that did descend from reptiles. And mammals did descend from tiktaalik that did descend from fish.That you don't see these facts, despite the weight of data points available in evidence, shows just how intellectually blind (via religion) you have become.The rest of your post was your personal butt-hurt tripe. I'll pass.

Kleinman:

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AZPaul3 believes that reptiles evolve into birds and fish evolve into mammals ...

AZPaul3:

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Wow. You almost got something right.
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Birds did descend from dinos that did descend from reptiles. And mammals did descend from tiktaalik that did descend from fish.
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That you don't see these facts, despite the weight of data points available in evidence, shows just how intellectually blind (via religion) you have become.
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The rest of your post was your personal butt-hurt tripe. I'll pass.

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Since AZPaul3 knows as much about descent with modification and adaptation as he knows about making a psychiatric diagnosis, he will now explain to us how drug resistance evolves and why cancer treatments fail. He won't and he can't because he only knows the stories that biologists have told him. And biologists don't know and have never explained how drug resistance evolves and why cancer treatments fail.

What a pity you can't prove that any of your atheist folklore is true. They're not facts, con-man ... they're theories. Don't you ever get tired ???? of telling lies?

Where did "????" come from?

Dunno.