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Author Topic:   Mutations Confirm Common Descent
Taq
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Posts: 9972
Joined: 03-06-2009
Member Rating: 5.6


Message 96 of 106 (907473)
02-24-2023 10:46 AM
Reply to: Message 94 by sensei
02-24-2023 3:51 AM


sensei writes:
That is the correct math for one dimensional random walk between two fixed boundaries. If the data would show different rates outside of the models confidence ranges, we may need to see if near extinction events could explain higher fixation for example, as fixation becomes more likely in smaller populations, with boundaries closer together.
In a bottleneck situation you would get a surge in fixed mutations, if memory servers. The dynamics of population size will definitely have an effect.

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 Message 94 by sensei, posted 02-24-2023 3:51 AM sensei has replied

Replies to this message:
 Message 97 by sensei, posted 03-08-2023 5:18 AM Taq has replied

  
Taq
Member
Posts: 9972
Joined: 03-06-2009
Member Rating: 5.6


Message 100 of 106 (908203)
03-09-2023 12:33 PM
Reply to: Message 97 by sensei
03-08-2023 5:18 AM


sensei writes:
I made these graphs.
I'm not seeing any images, sorry. EvC is picky on how it displays images. For most of my posts I use html code which seems to work most of the time. If you see one of my posts with pictures in it you can hit the peek button and see how I did it.
The model is for a single "neutral" DNA base, that can be A or B, so two possibilities instead of the usual four.
What does this have to do with the topic at hand? How does it relate to the opening posts?

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 Message 97 by sensei, posted 03-08-2023 5:18 AM sensei has replied

Replies to this message:
 Message 102 by sensei, posted 03-09-2023 1:34 PM Taq has replied

  
Taq
Member
Posts: 9972
Joined: 03-06-2009
Member Rating: 5.6


Message 103 of 106 (908232)
03-09-2023 1:46 PM
Reply to: Message 102 by sensei
03-09-2023 1:34 PM


sensei writes:
Do you see images or links to images now?
Yes, I see them.
Starting from a fixed DNA base, it takes millions of generations to reach equilibrium.

Depending on how much of DNA is junk or neutral, comparing DNA of two individuals and finding 99.9% similarity, seems very high, compared to my model for such large population.
Is it because we are still far from equilibrium?
I'm still not seeing the relationship between this model and what is presented in the opening posts. What does this have to do with the ratio of transition to transversion mutations?

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 Message 102 by sensei, posted 03-09-2023 1:34 PM sensei has replied

Replies to this message:
 Message 104 by sensei, posted 03-09-2023 2:58 PM Taq has replied

  
Taq
Member
Posts: 9972
Joined: 03-06-2009
Member Rating: 5.6


Message 105 of 106 (908249)
03-09-2023 3:41 PM
Reply to: Message 104 by sensei
03-09-2023 2:58 PM


sensei writes:
You are comparing DNA of primates and found that it fits predictions of a common ancestor.
Yes, and that prediction is the ratio of transition to transversion mutations, along with CpG transitions.
So I'm trying to see if other predictions fit as well.
If you want to discuss a different prediction then feel free to start a new thread.
Because we don't want to be cherry picking only data that fits our hypothesis now, I suppose.
We also don't want a Gish Gallop.
Or do you think it's better to start a new topic?
I do think that.

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 Message 104 by sensei, posted 03-09-2023 2:58 PM sensei has replied

Replies to this message:
 Message 106 by sensei, posted 03-16-2023 4:27 AM Taq has not replied

  
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