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Author Topic:   Why is evolution so controversial?
Taq
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Posts: 10033
Joined: 03-06-2009
Member Rating: 5.8


Message 917 of 969 (740674)
11-06-2014 3:40 PM
Reply to: Message 914 by zaius137
11-06-2014 2:55 PM


Re: Any real evidence for evolution, point on point.
I understand the papers I cited claim more than 1.5% divergence counting indels.
So does the chimp genome paper if you are counting number of bases instead of number of mutations. The chimp genome paper has 5 million indels covering 90 million bases compared to 35 million substitution mutations.
Are you still claiming they are wrong?
I am claiming that your interpretation of the papers is wrong.

This message is a reply to:
 Message 914 by zaius137, posted 11-06-2014 2:55 PM zaius137 has replied

Replies to this message:
 Message 918 by sfs, posted 11-06-2014 3:55 PM Taq has not replied
 Message 919 by zaius137, posted 11-06-2014 8:45 PM Taq has replied

  
Taq
Member
Posts: 10033
Joined: 03-06-2009
Member Rating: 5.8


(1)
Message 925 of 969 (740716)
11-06-2014 11:44 PM
Reply to: Message 919 by zaius137
11-06-2014 8:45 PM


Re: Any real evidence for evolution, point on point.
One thing is certain you do not want to count indel divergence as autosomal segment divergence.
That's exactly what the authors of the chimp genome paper did.
"Here we present a draft genome sequence of the common chimpanzee (Pan troglodytes). Through comparison with the human genome, we have generated a largely complete catalogue of the genetic differences that have accumulated since the human and chimpanzee species diverged from our common ancestor, constituting approximately thirty-five million single-nucleotide changes, five million insertion/deletion events, and various chromosomal rearrangements."
Initial sequence of the chimpanzee genome and comparison with the human genome | Nature
It is clear now that secular scientists have caught up to the fact that a human chimp divergence of 1.5% is nonsense.
That is the divergence due to substitutions, and continues to be.
Is it because you think there is not enough indels to count? If that is your point, it is in direct contradiction to my citations (I have at this point provided 6) that implicitly added them to substitution rates.
It is the way that you add them together that is wrong. The authors of the peer reviewed papers do it correctly.
I have tried and failed to correct your perspective of what constitutes a site as it relates to mutation.
You have failed because you are wrong. One indel is one mutation. A 5 base indel is 1 mutation, not 5. A sequence with 20 bases has 20 sites where a mutation can occur.
You have repeatedly mixed up (u) and (k) in the calculation I was using. That is rate and percentage divergence.
What are the units for divergence?
I will, at this point, let you name the additional divergence you think is acceptable. If you claim it is zero, argue with the secular scientists who say that it is more than zero.
I have already discussed the mutation rate with you multiple times. If you are going to use the 5% divergence as measured by differences in bases then you need to use a mutation rate that incorporates the number of bases changed per generation. You aren't doing that. The mutation rate needs to be about 250 bases changed per generation. You are using 70.

This message is a reply to:
 Message 919 by zaius137, posted 11-06-2014 8:45 PM zaius137 has replied

Replies to this message:
 Message 927 by zaius137, posted 11-07-2014 3:40 AM Taq has replied

  
Taq
Member
Posts: 10033
Joined: 03-06-2009
Member Rating: 5.8


Message 937 of 969 (740824)
11-07-2014 4:23 PM
Reply to: Message 927 by zaius137
11-07-2014 3:40 AM


Re: Any real evidence for evolution, point on point.
I do not know how you calculated 250 new mutations per generation . . .
I have given you this calculation several times now.
There are 70 new substitutions each generation. If the indel rate is 1/7th of that as sfs indicated, then that is 10 indels.
Indels can be more than one base. In fact, the average indel is ~20 bases. 10 indels at 20 bases each is 200 bases.
So we have 70 bases changed from substitutions and 200 bases changed from indels. 200 +70 is 270 bases changed per generation.
With a 5% autosomal sequence divergence between a human and chimp you need a mutation rate of ~5 x 10^-8 for 6 million years. That would be 320 new mutations per generation.
320 is very close to the 270 I just calculated.

This message is a reply to:
 Message 927 by zaius137, posted 11-07-2014 3:40 AM zaius137 has replied

Replies to this message:
 Message 941 by sfs, posted 11-07-2014 8:29 PM Taq has not replied
 Message 942 by zaius137, posted 11-08-2014 1:09 AM Taq has not replied

  
Taq
Member
Posts: 10033
Joined: 03-06-2009
Member Rating: 5.8


Message 938 of 969 (740826)
11-07-2014 4:27 PM
Reply to: Message 935 by zaius137
11-07-2014 12:50 PM


Re: Any real evidence for evolution, point on point.
That is how you calculate mutation rate using indels and SNPs.
Notice that they used number of mutations instead of number of bases changed.
If you are going to follow their lead, then you can't use the 5% figure. When you use number of mutations the indels count as 1 mutation instead of multiple bases.

This message is a reply to:
 Message 935 by zaius137, posted 11-07-2014 12:50 PM zaius137 has not replied

  
Taq
Member
Posts: 10033
Joined: 03-06-2009
Member Rating: 5.8


Message 939 of 969 (740828)
11-07-2014 4:28 PM
Reply to: Message 936 by zaius137
11-07-2014 12:56 PM


Re: A real (k)
Now knowing the combined (u) (1.1 x10^-8) we can calculate the combined (k) for humans or what it should be.
What are the units? Number of bases, or number of mutations?

This message is a reply to:
 Message 936 by zaius137, posted 11-07-2014 12:56 PM zaius137 has replied

Replies to this message:
 Message 944 by zaius137, posted 11-08-2014 1:19 AM Taq has replied

  
Taq
Member
Posts: 10033
Joined: 03-06-2009
Member Rating: 5.8


Message 940 of 969 (740832)
11-07-2014 4:33 PM
Reply to: Message 934 by zaius137
11-07-2014 12:10 PM


Re: Any real evidence for evolution, point on point.
That is just funny...
The funniest part is that you are trying to claim that the theory of evolution will fall apart once we add in the indels.
I took your challenge and added the indels to substitutions for the mutation rate.
What happened? You complained about the indels being added to the substitutions.
Irony?

This message is a reply to:
 Message 934 by zaius137, posted 11-07-2014 12:10 PM zaius137 has replied

Replies to this message:
 Message 946 by zaius137, posted 11-08-2014 10:36 AM Taq has not replied

  
Taq
Member
Posts: 10033
Joined: 03-06-2009
Member Rating: 5.8


(3)
Message 967 of 969 (742176)
11-17-2014 5:46 PM
Reply to: Message 944 by zaius137
11-08-2014 1:19 AM


Re: A real (k)
Settling this once and for all a rate of 1.1 x 10-8 mutations per base pair per generation.
Then you can't use a divergence of 5% since that is not the number of mutations, but the number of bases that differ between the two.

This message is a reply to:
 Message 944 by zaius137, posted 11-08-2014 1:19 AM zaius137 has not replied

  
Taq
Member
Posts: 10033
Joined: 03-06-2009
Member Rating: 5.8


(2)
Message 968 of 969 (742177)
11-17-2014 5:47 PM
Reply to: Message 956 by zaius137
11-10-2014 2:00 AM


Re: sfs in a vacuum.
Ask the authors of the papers claiming that you can add indels to divergence.
The authors of the paper can and do add them together correctly. That is why they get the proper divergence times.
The problem is that YOU can't add them correctly. That is why you get different results than the authors do.
Edited by Taq, : No reason given.
Edited by Taq, : No reason given.

This message is a reply to:
 Message 956 by zaius137, posted 11-10-2014 2:00 AM zaius137 has not replied

  
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