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Topic: The Nature of Mutations
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Message 331 of 344 (44538)
06-28-2003 4:00 PM
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Message 332 of 344 (44539)
06-28-2003 4:00 PM
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Message 333 of 344 (44540)
06-28-2003 4:00 PM
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Message 334 of 344 (44541)
06-28-2003 4:00 PM
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Message 335 of 344 (44542)
06-28-2003 4:00 PM
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Message 336 of 344 (44543)
06-28-2003 4:00 PM
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John A. Davison 
Inactive Member
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Message 337 of 344 (44596)
06-29-2003 7:38 AM
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Reply to: Message 336 by Unknown Author
06-28-2003 4:00 PM
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Re: evidence from cytogenetics
Mr. P. As usual, reading comprehension is the difficulty. M.J.D. White in no uncertain language made it very clear that many, including virtually all the chromosome rearrangements in Drosophila, were not produced through sexual reproduction. After presenting three of his unmistakable quotations, which I can only assume you dismiss, I offer my conclusion: "I submit that if they were not produced sexually, there remains only one other conceivable way they could have been produced and that is semi-meiotically as I have indicated. If there is another way, I can only hope that someone will enlighten me!" Furthermore, I have never maintained that one cannot produce chromosome rearrangements through sexual reproduction and I resent your inferences. Also, the reasons I have not published any conclusions verifying the semi-meiotic hypothesis are of no concern to you or anyone else. I have never published a paper about which I had any reservations and I am not about to start now. I know how certain members of this forum loathe my use of direct quotation as it leaves no question of what the source meant and we can't have that of course. So I leave you with one from Oscar Wilde :"If you tell the truth you can be certain, sooner or later, to be found out". salty
| This message is a reply to: | | | Message 336 by Unknown Author, posted 06-28-2003 4:00 PM | | Unknown Author has not replied |
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Wounded King
Member (Idle past 287 days) Posts: 4149 From: Cincinnati, Ohio, USA Joined: 04-09-2003
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Message 338 of 344 (44597)
06-29-2003 7:39 AM
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Reply to: Message 335 by Unknown Author
06-28-2003 4:00 PM
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Dear Salty, A recent paper in 'Development' has shown a number of developmental defects in C. elegans associated with defects in meiosis. These defects are caused by RNAi knockout of the Anaphase promoting complex (APC) and include cases where only meiosis 1 occurs and meiosis 2 is skipped entirely.
Development. 2003 Apr;130(8):1605-20.
Developmental defects observed in hypomorphic anaphase-promoting complex mutants are linked to cell cycle abnormalities.
Shakes DC, Sadler PL, Schumacher JM, Abdolrasulnia M, Golden A. I was wondering if you were aware of this work and if you felt it was in line with, or in deed at all relevant to, your own theories. Cheers, Wounded
| This message is a reply to: | | | Message 335 by Unknown Author, posted 06-28-2003 4:00 PM | | Unknown Author has not replied |
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John A. Davison
Inactive Member
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Thank you wounded, I will look into it. salty
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John A. Davison
Inactive Member
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Mr. P. What ever happened to your post number 336 to which I replied with post 337? I thought you people never deleted posts. I request an explanation for this bizarre occurrence. salty
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John A. Davison
Inactive Member
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missing posts.
There seems to be quite a hiatus in posts extending from 315 to 336. What is going on? salty
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Adminnemooseus
Inactive Administrator
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Message 342 of 344 (44617)
06-29-2003 1:57 PM
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What we have here is a damaged topic. I will close it for now. Hopefully Admin will be able to fix it or restore it from a backup. Adminnemooseus
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Admin
Director Posts: 13107 From: EvC Forum Joined: 06-14-2002
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Message 343 of 344 (44714)
06-30-2003 3:34 PM
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Sometimes forces beyond out ken just reach out of the ether to smite us. I will do what I can to restore this thread, but it doesn't seem likely at this point. I apologize for the inconvenience. Please resume discussion in the The Nature of Mutations II thread. ------------------ --Percy EvC Forum Administrator
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Adminnemooseus
Inactive Administrator
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Message 344 of 344 (45482)
07-09-2003 4:30 AM
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Final possible repairs are done
I did some message by message editing on page 14, from information in the Google cache. Admin had already done a fine job of repairing pages 15 through 19, and 21 and 22. Pages 20 and 23 still have missing messages. We have nowhere to recover that stuff. Cheers - Topic now closed once again. Adminnemooseus
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