1) the reliability of clinical diagnoses,...
Recently the tools of genetics and CTscans have been added to the diagnostic kit. This allows researchers to see if there is something common between people with certain diseases determined by classical diagnosis.
This is fairly new but is showing some results. It is probably most hindered by having to use classical diagnosis for data organization when that is the least reliable of the techniques.
I expect psychology to grow up soon. Especially for things like battle fatigue (where we now have a large source of people to study).
Enjoy.
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